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Found 22 Enz. Inhib. hit(s) with all data for entry = 50009900
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Hinoki Shinyaku

Curated by ChEMBL
LigandPNGBDBM50145829(4-Aminobenzoesaeure | 4-aminobenzoic acid | CHEMBL...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate assessed as dopachrome formation preincubated for 10 mins followed by protein additio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Hinoki Shinyaku

Curated by ChEMBL
LigandPNGBDBM50145829(4-Aminobenzoesaeure | 4-aminobenzoic acid | CHEMBL...)
Affinity DataIC50:  3.80E+3nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate assessed as dopachrome formation preincubated for 10 mins followed by protein additio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Hinoki Shinyaku

Curated by ChEMBL
LigandPNGBDBM50195793(CHEMBL123234)
Affinity DataIC50:  6.97E+3nMAssay Description:Inhibition of mushroom tyrosinase monophenolase activity using L-tyrosine as substrate measured every 60 s for 25 timesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Hinoki Shinyaku

Curated by ChEMBL
LigandPNGBDBM50195793(CHEMBL123234)
Affinity DataIC50:  6.97E+3nMAssay Description:Inhibition of mushroom tyrosinase monophenolase activity using L-tyrosine as substrate measured every 60 s for 25 timesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Hinoki Shinyaku

Curated by ChEMBL
LigandPNGBDBM50195793(CHEMBL123234)
Affinity DataIC50:  3.63E+4nMAssay Description:Inhibition of mushroom tyrosinase diphenolase activity using L-DOPA as substrate measured every 30 s for 25 timesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Hinoki Shinyaku

Curated by ChEMBL
LigandPNGBDBM50195793(CHEMBL123234)
Affinity DataIC50:  3.63E+4nMAssay Description:Inhibition of mushroom tyrosinase diphenolase activity using L-DOPA as substrate measured every 30 s for 25 timesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Hinoki Shinyaku

Curated by ChEMBL
LigandPNGBDBM50060971(Biphenyl-4-carboxylic acid | CHEMBL107057)
Affinity DataIC50:  6.32E+4nMAssay Description:Inhibition of mushroom tyrosinase monophenolase activity using L-tyrosine as substrate measured every 60 s for 25 timesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Hinoki Shinyaku

Curated by ChEMBL
LigandPNGBDBM50060971(Biphenyl-4-carboxylic acid | CHEMBL107057)
Affinity DataIC50:  6.32E+4nMAssay Description:Inhibition of mushroom tyrosinase monophenolase activity using L-tyrosine as substrate measured every 60 s for 25 timesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Hinoki Shinyaku

Curated by ChEMBL
LigandPNGBDBM50060971(Biphenyl-4-carboxylic acid | CHEMBL107057)
Affinity DataIC50:  2.16E+5nMAssay Description:Inhibition of mushroom tyrosinase diphenolase activity using L-DOPA as substrate measured every 30 s for 25 timesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Hinoki Shinyaku

Curated by ChEMBL
LigandPNGBDBM50060971(Biphenyl-4-carboxylic acid | CHEMBL107057)
Affinity DataIC50:  2.16E+5nMAssay Description:Inhibition of mushroom tyrosinase diphenolase activity using L-DOPA as substrate measured every 30 s for 25 timesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Hinoki Shinyaku

Curated by ChEMBL
LigandPNGBDBM197302(Benzoic acid | SAMPL4, O1)
Affinity DataIC50:  2.25E+5nMAssay Description:Inhibition of mushroom tyrosinase monophenolase activity using L-tyrosine as substrate measured every 60 s for 25 timesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Hinoki Shinyaku

Curated by ChEMBL
LigandPNGBDBM197302(Benzoic acid | SAMPL4, O1)
Affinity DataIC50:  2.25E+5nMAssay Description:Inhibition of mushroom tyrosinase monophenolase activity using L-tyrosine as substrate measured every 60 s for 25 timesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Hinoki Shinyaku

Curated by ChEMBL
LigandPNGBDBM243072(Anisic acid)
Affinity DataIC50:  4.20E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate assessed as dopachrome formation preincubated for 10 mins followed by protein additio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Hinoki Shinyaku

Curated by ChEMBL
LigandPNGBDBM243072(Anisic acid)
Affinity DataIC50:  4.20E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-tyrosine as substrate assessed as dopachrome formation preincubated for 10 mins followed by protein additio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Hinoki Shinyaku

Curated by ChEMBL
LigandPNGBDBM197302(Benzoic acid | SAMPL4, O1)
Affinity DataIC50:  7.10E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 5 mins followed by substrate addition measured for 2 mins by spectrophot...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Hinoki Shinyaku

Curated by ChEMBL
LigandPNGBDBM197302(Benzoic acid | SAMPL4, O1)
Affinity DataIC50:  7.10E+5nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate preincubated for 5 mins followed by substrate addition measured for 2 mins by spectrophot...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Hinoki Shinyaku

Curated by ChEMBL
LigandPNGBDBM197302(Benzoic acid | SAMPL4, O1)
Affinity DataIC50:  8.22E+5nMAssay Description:Inhibition of mushroom tyrosinase diphenolase activity using L-DOPA as substrate measured every 30 s for 25 timesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Hinoki Shinyaku

Curated by ChEMBL
LigandPNGBDBM197302(Benzoic acid | SAMPL4, O1)
Affinity DataIC50:  8.22E+5nMAssay Description:Inhibition of mushroom tyrosinase diphenolase activity using L-DOPA as substrate measured every 30 s for 25 timesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Hinoki Shinyaku

Curated by ChEMBL
LigandPNGBDBM50533338(CHEMBL3092388)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of mushroom tyrosinase monophenolase activity using L-tyrosine as substrate measured every 60 s for 25 timesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Hinoki Shinyaku

Curated by ChEMBL
LigandPNGBDBM50533338(CHEMBL3092388)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of mushroom tyrosinase monophenolase activity using L-tyrosine as substrate measured every 60 s for 25 timesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Hinoki Shinyaku

Curated by ChEMBL
LigandPNGBDBM50533338(CHEMBL3092388)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of mushroom tyrosinase diphenolase activity using L-DOPA as substrate measured every 30 s for 25 timesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
Hinoki Shinyaku

Curated by ChEMBL
LigandPNGBDBM50533338(CHEMBL3092388)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of mushroom tyrosinase diphenolase activity using L-DOPA as substrate measured every 30 s for 25 timesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed