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Found 12 Enz. Inhib. hit(s) with all data for entry = 50049060
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50396097(CHEMBL2170856)
Affinity DataIC50:  230nMAssay Description:Inhibition of telomerase activity in human MDA-MB-435 cell lysate measured after 24 hrs by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50396097(CHEMBL2170856)
Affinity DataIC50:  230nMAssay Description:Inhibition of telomerase activity in human U2OS cell lysate measured after 24 hrs by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50157547(2-(3,4-dihydroxyphenyl)-7,8-dihydroxy-4H-chromen-4...)
Affinity DataIC50:  740nMAssay Description:Inhibition of telomerase activity (unknown origin) in cell free system using sulforhodamine labeled primer measured after 30 mins by telomerase repea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50233825(CHEMBL4081286)
Affinity DataIC50:  969nMAssay Description:Inhibition of telomerase activity (unknown origin) in cell free system using sulforhodamine labeled primer measured after 30 mins by telomerase repea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50233823(CHEMBL4097807)
Affinity DataIC50:  1.58E+3nMAssay Description:Inhibition of telomerase activity in human U2OS cell lysate measured after 24 hrs by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50233823(CHEMBL4097807)
Affinity DataIC50:  1.58E+3nMAssay Description:Inhibition of telomerase activity in human MDA-MB-435 cell lysate measured after 24 hrs by TRAP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50233826(CHEMBL4090090)
Affinity DataIC50:  1.65E+3nMAssay Description:Inhibition of telomerase activity (unknown origin) in cell free system using sulforhodamine labeled primer measured after 30 mins by telomerase repea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50233824(CHEMBL4070673)
Affinity DataIC50:  1.73E+3nMAssay Description:Inhibition of telomerase activity (unknown origin) in cell free system using sulforhodamine labeled primer measured after 30 mins by telomerase repea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50126186(2-(3-Naphthalen-2-yl-but-2-enoylamino)-benzoic aci...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of human telomerase activity isolated from HEK293 cells assessed as reduction in dNTP incorporation using 5'-biotinylated AATCCGTCGAGCAGAG...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50126186(2-(3-Naphthalen-2-yl-but-2-enoylamino)-benzoic aci...)
Affinity DataIC50:  1.16E+4nMAssay Description:Inhibition of telomerase activity (unknown origin) in cell free system using sulforhodamine labeled primer measured after 30 mins by telomerase repea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50233827(CHEMBL4076246)
Affinity DataIC50:  2.81E+4nMAssay Description:Inhibition of telomerase activity (unknown origin) in cell free system using sulforhodamine labeled primer measured after 30 mins by telomerase repea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTelomerase reverse transcriptase(Homo sapiens (Human))
University Of Oxford

Curated by ChEMBL
LigandPNGBDBM50233828(CHEMBL4062047)
Affinity DataIC50:  3.01E+4nMAssay Description:Inhibition of telomerase activity (unknown origin) in cell free system using sulforhodamine labeled primer measured after 30 mins by telomerase repea...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed