Found 42 Enz. Inhib. hit(s) with all data for entry = 50049180 
Affinity DataIC50: 3nMAssay Description:Inhibitory concentration against cyclin dependent kinase-2 (CDK2)/Cyclin EMore data for this Ligand-Target Pair
Affinity DataIC50: 4.30nMAssay Description:Inhibition of human plasma BuChE using S-butyrylthiocholine iodide as substrate preincubated for 60 mins followed by substrate addition measured afte...More data for this Ligand-Target Pair
Affinity DataIC50: 7.10nMAssay Description:Inhibitory concentration against cyclin dependent kinase-2 (CDK2)/Cyclin EMore data for this Ligand-Target Pair
Affinity DataIC50: 7.30nMAssay Description:Inhibitory concentration against cyclin dependent kinase-2 (CDK2)/Cyclin EMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibitory concentration against cyclin dependent kinase-2 (CDK2)/Cyclin EMore data for this Ligand-Target Pair
Affinity DataIC50: 108nMAssay Description:Tested for its ability to compete with [125I]C5a for binding to C5a anaphylatoxin chemotactic receptor of human neutrophil membrane preparationsMore data for this Ligand-Target Pair
Affinity DataIC50: 113nMAssay Description:Inhibitory concentration against cyclin dependent kinase-2 (CDK2)/Cyclin EMore data for this Ligand-Target Pair
Affinity DataIC50: 116nMAssay Description:Inhibitory concentration against cyclin dependent kinase-2 (CDK2)/Cyclin EMore data for this Ligand-Target Pair
Affinity DataIC50: 119nMAssay Description:Inhibition of equine serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 60 mins followed by substrate addition measured afte...More data for this Ligand-Target Pair
Affinity DataIC50: 126nMAssay Description:Compound was tested for its ability to inhibit the neurotransmitter serotonin-5-HT reuptake system using [3H]5-HT as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of equine serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 60 mins followed by substrate addition measured afte...More data for this Ligand-Target Pair
Affinity DataIC50: 224nMAssay Description:Inhibitory concentration against cyclin dependent kinase-2 (CDK2)/Cyclin EMore data for this Ligand-Target Pair
Affinity DataIC50: 253nMAssay Description:Inhibitory concentration against cyclin dependent kinase-2 (CDK2)/Cyclin EMore data for this Ligand-Target Pair
Affinity DataIC50: 476nMAssay Description:Norepinephrine transporter activity was determined by the ability of compound to inhibit the neurotransmitter norepinephrine-NE reuptake system using...More data for this Ligand-Target Pair
Affinity DataIC50: 686nMAssay Description:Inhibition of equine serum BuChE using S-butyrylthiocholine iodide as substrate preincubated for 60 mins followed by substrate addition measured afte...More data for this Ligand-Target Pair
Affinity DataIC50: 1.13E+3nMAssay Description:Tested for its ability to compete with [125I]C5a for binding to C5a anaphylatoxin chemotactic receptor of human neutrophil membrane preparationsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Tested for the ability to compete with [125I]-CO13 ([125I]-Y-F-K-A-Cha-G-L-dF-R) for binding to C5a anaphylatoxin chemotactic receptor from human neu...More data for this Ligand-Target Pair
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibitory concentration against cyclin dependent kinase-2 (CDK2)/Cyclin EMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
South China University Of Technology
Curated by ChEMBL
South China University Of Technology
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Tested for its ability to compete with [125I]C5a for binding to C5a anaphylatoxin chemotactic receptor of human neutrophil membrane preparationsMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
South China University Of Technology
Curated by ChEMBL
South China University Of Technology
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human erythrocytes AChE using S-acetylthiocholine iodide as substrate preincubated for 60 mins followed by substrate addition measured ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
South China University Of Technology
Curated by ChEMBL
South China University Of Technology
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human erythrocytes AChE using S-acetylthiocholine iodide as substrate preincubated for 60 mins followed by substrate addition measured ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Homo sapiens (Human))
South China University Of Technology
Curated by ChEMBL
South China University Of Technology
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory concentration against cyclin dependent kinase-2 (CDK2)/Cyclin EMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
South China University Of Technology
Curated by ChEMBL
South China University Of Technology
Curated by ChEMBL
Affinity DataIC50: 4.13E+4nMAssay Description:Inhibition of electric eel AChE using S-acetylthiocholine iodide as substrate preincubated for 60 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
South China University Of Technology
Curated by ChEMBL
South China University Of Technology
Curated by ChEMBL
Affinity DataIC50: 6.60E+4nMAssay Description:Compound was tested for its ability to inhibit the neurotransmitter dopamine-DA reuptake system using [3H]dopamine as radioligandMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
South China University Of Technology
Curated by ChEMBL
South China University Of Technology
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of electric eel AChE using S-acetylthiocholine iodide as substrate preincubated for 60 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
South China University Of Technology
Curated by ChEMBL
South China University Of Technology
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of electric eel AChE using S-acetylthiocholine iodide as substrate preincubated for 60 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
South China University Of Technology
Curated by ChEMBL
South China University Of Technology
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of electric eel AChE using S-acetylthiocholine iodide as substrate preincubated for 60 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
South China University Of Technology
Curated by ChEMBL
South China University Of Technology
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of electric eel AChE using S-acetylthiocholine iodide as substrate preincubated for 60 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
South China University Of Technology
Curated by ChEMBL
South China University Of Technology
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of electric eel AChE using S-acetylthiocholine iodide as substrate preincubated for 60 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
South China University Of Technology
Curated by ChEMBL
South China University Of Technology
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Tested for its ability to compete with [125I]C5a for binding to C5a anaphylatoxin chemotactic receptor of human neutrophil membrane preparationsMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
South China University Of Technology
Curated by ChEMBL
South China University Of Technology
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of electric eel AChE using S-acetylthiocholine iodide as substrate preincubated for 60 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
South China University Of Technology
Curated by ChEMBL
South China University Of Technology
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of electric eel AChE using S-acetylthiocholine iodide as substrate preincubated for 60 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
South China University Of Technology
Curated by ChEMBL
South China University Of Technology
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of electric eel AChE using S-acetylthiocholine iodide as substrate preincubated for 60 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
South China University Of Technology
Curated by ChEMBL
South China University Of Technology
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of electric eel AChE using S-acetylthiocholine iodide as substrate preincubated for 60 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
South China University Of Technology
Curated by ChEMBL
South China University Of Technology
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Antagonism of batrachotoxin-mediated sodium ion uptake into cultured neuroblastoma cellsMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
South China University Of Technology
Curated by ChEMBL
South China University Of Technology
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Antagonism of batrachotoxin-mediated sodium ion uptake into cultured neuroblastoma cellsMore data for this Ligand-Target Pair
Affinity DataKoff: 1.00E+5s-1Assay Description:Irreversible inhibition of human plasma BuChE assessed as second order carbamylation rate constant using S-butyrylthiocholine iodide as substrate pre...More data for this Ligand-Target Pair
Affinity DataKoff: 1.30E+5s-1Assay Description:Antagonism of batrachotoxin-mediated sodium ion uptake into cultured neuroblastoma cellsMore data for this Ligand-Target Pair
Affinity DataKoff: 2.48E+3s-1Assay Description:Antagonism of batrachotoxin-mediated sodium ion uptake into cultured neuroblastoma cellsMore data for this Ligand-Target Pair
Affinity DataKoff: 2.37E+3s-1Assay Description:Irreversible inhibition of equine serum BuChE assessed as second order carbamylation rate constant using S-butyrylthiocholine iodide as substrate pre...More data for this Ligand-Target Pair
Affinity DataKoff: 2.40E+3s-1Assay Description:Antagonism of batrachotoxin-mediated sodium ion uptake into cultured neuroblastoma cellsMore data for this Ligand-Target Pair
Affinity DataKoff: 1.22E+5s-1Assay Description:Tested for the ability to compete with [125I]-CO13 ([125I]-Y-F-K-A-Cha-G-L-dF-R) for binding to C5a anaphylatoxin chemotactic receptor from human neu...More data for this Ligand-Target Pair
