Compile Data Set for Download or QSAR
maximum 50k data
Found 109 Enz. Inhib. hit(s) with all data for entry = 50001937
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50161518(1-(oxazolo[4,5-b]pyridin-2-yl)-6-phenylhexan-1-one...)
Affinity DataKi:  0.200nMAssay Description:Inhibition of rat FAAH assessed as reduction in [14C]oleamide conversion to oleic acid by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM23316(7-phenyl-1-{pyrido[2,3-d][1,3]oxazol-2-yl}heptan-1...)
Affinity DataKi:  0.280nMAssay Description:Inhibition of rat FAAH assessed as reduction in [14C]oleamide conversion to oleic acid by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50275119(1-(oxazolo[4,5-b]pyridin-2-yl)-5-phenylpentan-1-on...)
Affinity DataKi:  0.300nMAssay Description:Inhibition of rat FAAH assessed as reduction in [14C]oleamide conversion to oleic acid by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50161520(1-(oxazolo[4,5-b]pyridin-2-yl)-8-phenyloctan-1-one...)
Affinity DataKi:  0.390nMAssay Description:Inhibition of rat FAAH assessed as reduction in [14C]oleamide conversion to oleic acid by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50161525(1-(oxazolo[4,5-b]pyridin-2-yl)-9-phenylnonan-1-one...)
Affinity DataKi:  0.520nMAssay Description:Inhibition of rat FAAH assessed as reduction in [14C]oleamide conversion to oleic acid by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50350547(CHEMBL257307)
Affinity DataKi:  0.570nMAssay Description:Inhibition of rat FAAH assessed as reduction in [14C]oleamide conversion to oleic acid by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50350545(CHEMBL257305)
Affinity DataKi:  0.690nMAssay Description:Inhibition of rat FAAH assessed as reduction in [14C]oleamide conversion to oleic acid by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50350546(CHEMBL1812708)
Affinity DataKi:  0.75nMAssay Description:Inhibition of rat FAAH assessed as reduction in [14C]oleamide conversion to oleic acid by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50100865((Z)-1-(oxazolo[4,5-b]pyridin-2-yl)octadec-9-en-1-o...)
Affinity DataKi:  2.30nMAssay Description:Inhibition of rat FAAH assessed as reduction in [14C]oleamide conversion to oleic acid by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50350554(CHEMBL272770)
Affinity DataKi:  3.70nMAssay Description:Inhibition of rat FAAH assessed as reduction in [14C]oleamide conversion to oleic acid by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50350555(CHEMBL1812590)
Affinity DataKi:  7.20nMAssay Description:Inhibition of rat FAAH assessed as reduction in [14C]oleamide conversion to oleic acid by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50350556(CHEMBL1812591)
Affinity DataKi:  11nMAssay Description:Inhibition of rat FAAH assessed as reduction in [14C]oleamide conversion to oleic acid by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM22988((5Z,8Z,11Z,14Z)-N-(2-hydroxyethyl)icosa-5,8,11,14-...)
Affinity DataKi:  50nMAssay Description:Binding affinity to CB1R (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50100871((Z)-1-(benzo[d]oxazol-2-yl)octadec-9-en-1-one | (Z...)
Affinity DataKi:  370nMAssay Description:Inhibition of rat FAAH assessed as reduction in [14C]oleamide conversion to oleic acid by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM26144(1,3-dihydroxypropan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8...)
Affinity DataKi:  1.00E+3nMAssay Description:Binding affinity to CB1R (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Mus musculus (mouse))
Universit£

Curated by ChEMBL
LigandPNGBDBM50450752(CHEMBL4216513)
Affinity DataIC50:  0.191nMAssay Description:Inhibition of mouse MAGLMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50065646(CHEMBL3087181)
Affinity DataIC50:  0.214nMAssay Description:Inhibition of rat MAGLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Mus musculus (mouse))
Universit£

Curated by ChEMBL
LigandPNGBDBM50099618(CHEMBL1232635)
Affinity DataIC50:  0.219nMAssay Description:Inhibition of mouse MAGLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50450752(CHEMBL4216513)
Affinity DataIC50:  0.269nMAssay Description:Inhibition of rat MAGLMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Mus musculus (mouse))
Universit£

Curated by ChEMBL
LigandPNGBDBM50065646(CHEMBL3087181)
Affinity DataIC50:  0.275nMAssay Description:Inhibition of mouse MAGLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Mus musculus (mouse))
Universit£

Curated by ChEMBL
LigandPNGBDBM50102829(CHEMBL3356956)
Affinity DataIC50:  0.309nMAssay Description:Inhibition of mouse MAGLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50065646(CHEMBL3087181)
Affinity DataIC50:  0.363nMAssay Description:Inhibition of human MAGLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50450752(CHEMBL4216513)
Affinity DataIC50:  0.562nMAssay Description:Inhibition of human MAGLMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50102829(CHEMBL3356956)
Affinity DataIC50:  0.589nMAssay Description:Inhibition of rat MAGLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50099618(CHEMBL1232635)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of rat MAGLMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM179950(US9133148, 3a)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of recombinant human full length MAGL expressed in HEK293 cells preincubated for 30 mins followed by FP-Rh addition after 30 mins by gel-b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Mus musculus (mouse))
Universit£

Curated by ChEMBL
LigandPNGBDBM50450707(CHEMBL4215558)
Affinity DataIC50:  3.80nMAssay Description:Inhibition of mouse MAGLMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM26739(3-(3-carbamoylphenyl)phenyl N-cyclohexylcarbamate ...)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of FAAH in Wistar rat brain membranes using [3H]-anandamide as substrate preincubated for 10 mins followed by substrate addition measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM26739(3-(3-carbamoylphenyl)phenyl N-cyclohexylcarbamate ...)
Affinity DataIC50:  5nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged/C-terminal Myc-His6 tagged FAAH2 (32 to 579 residues) expressed in COS7 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50450750(CHEMBL4216931)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of rat brain microsomal FAAH using N-(2-hydroxyethyl)-4-pyren-1-yl-butanamide as substrate after 60 mins by RP HPLC based fluorescence ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50450760(CHEMBL4218592)
Affinity DataIC50:  5.80nMAssay Description:Inhibition of Sprague-Dawley rat brain FAAH preincubated for 10 mins followed by [3H]-anandamide substrate addition after 30 mins by liquid scintilla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM179929(US9133148, 1a)
Affinity DataIC50:  5.90nMAssay Description:Inhibition of recombinant human full length MAGL expressed in HEK293 cells preincubated for 30 mins followed by FP-Rh addition after 30 mins by gel-b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50450755(CHEMBL2171701)
Affinity DataIC50:  6.10nMAssay Description:Inhibition of rat FAAHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM179955(US9133148, 3f)
Affinity DataIC50:  6.90nMAssay Description:Inhibition of recombinant human full length MAGL expressed in HEK293 cells preincubated for 30 mins followed by FP-Rh addition after 30 mins by gel-b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Mus musculus (mouse))
Universit£

Curated by ChEMBL
LigandPNGBDBM179950(US9133148, 3a)
Affinity DataIC50:  7.60nMAssay Description:Inhibition of mouse MAGL preincubated for 30 mins followed by FP-Rh addition after 30 mins by gel-based ABPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
Universit£

Curated by ChEMBL
LigandPNGBDBM50450764(CHEMBL4218039)
Affinity DataIC50:  9nMAssay Description:Inhibition of CD1 mouse FAAHMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50450754(CHEMBL4202707)
Affinity DataIC50:  10nMAssay Description:Inhibition of FAAH (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50450758(CHEMBL4209606)
Affinity DataIC50:  11nMAssay Description:Inhibition of rat brain microsomal FAAH using N-(2-hydroxyethyl)-4-pyren-1-yl-butanamide as substrate after 60 mins by RP HPLC based fluorescence ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Mus musculus (mouse))
Universit£

Curated by ChEMBL
LigandPNGBDBM26736(CHEMBL509860 | LY2183240 | N,N-dimethyl-5-[(4-phen...)
Affinity DataIC50:  12nMAssay Description:Inhibition of mouse brain membrane FAAH preincubated for 10 mins followed by 14C-oleamide substrate addition measured up to 60 mins by TLC analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM23120(7-phenyl-1-[5-(pyridin-2-yl)-1,3-oxazol-2-yl]hepta...)
Affinity DataIC50:  13nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged/C-terminal Myc-His6 tagged FAAH2 (32 to 579 residues) expressed in COS7 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50396293(CHEMBL94809)
Affinity DataIC50:  13nMAssay Description:Inhibition of Sprague-Dawley rat brain FAAH using [14C]anandamide as substrate by liquid scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM179950(US9133148, 3a)
Affinity DataIC50:  14nMAssay Description:Inhibition of rat MAGL preincubated for 30 mins followed by FP-Rh addition after 30 mins by gel-based ABPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Mus musculus (mouse))
Universit£

Curated by ChEMBL
LigandPNGBDBM179929(US9133148, 1a)
Affinity DataIC50:  15nMAssay Description:Inhibition of mouse MAGL preincubated for 30 mins followed by FP-Rh addition after 30 mins by gel-based ABPP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM26740(N-phenyl-4-(quinolin-3-ylmethyl)piperidine-1-carbo...)
Affinity DataIC50:  16nMAssay Description:Inhibition of recombinant human N-terminal -His6 tagged FAAH (32 to 579 residues) expressed in Escherichia coli BL21 preincubated for 60 mins followe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Rattus norvegicus (Rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50359050(CHEMBL1922513)
Affinity DataIC50:  20nMAssay Description:Inhibition of recombinant rat N-terminal histidine tagged MAGL expressed in Escherichia coli Rosetta 2 (DE3) pLysS cells preincubated for 10 mins fol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50128585(CHEMBL431202 | Cyclohexyl-carbamic acid biphenyl-3...)
Affinity DataIC50:  26nMAssay Description:Inhibition of FAAH in Wistar rat brain membranes using [3H]-anandamide as substrate preincubated for 10 mins followed by substrate addition measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50450762(CHEMBL4213655)
Affinity DataIC50:  26nMAssay Description:Inhibition of Sprague-Dawley rat brain FAAH preincubated for 10 mins followed by [3H]-anandamide substrate addition after 30 mins by liquid scintilla...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetN-acylethanolamine-hydrolyzing acid amidase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50151057(CHEMBL3770726)
Affinity DataIC50:  27nMAssay Description:Inhibition recombinant human NAAA expressed in HEK293 cells after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM50437227(CHEMBL2402927 | US9187413, 1b (URB937))
Affinity DataIC50:  27nMAssay Description:Inhibition of FAAH in Wistar rat brain membranes using [3H]-anandamide as substrate preincubated for 10 mins followed by substrate addition measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50450707(CHEMBL4215558)
Affinity DataIC50:  29nMAssay Description:Inhibition of human MAGLMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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