Compile Data Set for Download or QSAR
maximum 50k data
Found 23 Enz. Inhib. hit(s) with all data for entry = 50048236
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50209639(CHEMBL3884057)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of recombinant human His6/GST-tagged SIRT1 expressed in Escherichia coli assessed as reduction in H2N-HK-[Nepsilon-acetyl-lysine]-LM-COOH ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50209638(CHEMBL3883974)
Affinity DataIC50:  1.24E+4nMAssay Description:Inhibition of recombinant human His6/GST-tagged SIRT1 expressed in Escherichia coli assessed as reduction in H2N-HK-[Nepsilon-acetyl-lysine]-LM-COOH ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50209637(CHEMBL3883503)
Affinity DataIC50:  1.46E+4nMAssay Description:Inhibition of recombinant human His6/GST-tagged SIRT1 expressed in Escherichia coli assessed as reduction in H2N-HK-[Nepsilon-acetyl-lysine]-LM-COOH ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50209633(CHEMBL3884174)
Affinity DataIC50:  1.46E+4nMAssay Description:Inhibition of recombinant human His6/GST-tagged SIRT1 expressed in Escherichia coli assessed as reduction in H2N-HK-[Nepsilon-acetyl-lysine]-LM-COOH ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50209649(CHEMBL3884090)
Affinity DataIC50:  1.54E+4nMAssay Description:Inhibition of recombinant human His6/GST-tagged SIRT1 expressed in Escherichia coli assessed as reduction in H2N-HK-[Nepsilon-acetyl-lysine]-LM-COOH ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50209641(CHEMBL3884328)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of recombinant human His6/GST-tagged SIRT1 expressed in Escherichia coli assessed as reduction in H2N-HK-[Nepsilon-acetyl-lysine]-LM-COOH ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50209631(CHEMBL3885246)
Affinity DataIC50:  2.22E+4nMAssay Description:Inhibition of recombinant human His6-tagged SIRT2 (2 to 389 residues) expressed in Escherichia coli assessed as inhibition of H2N-HK-[epsilonN-acetyl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50209643(CHEMBL3883379)
Affinity DataIC50:  2.70E+4nMAssay Description:Inhibition of recombinant human His6/GST-tagged SIRT1 expressed in Escherichia coli assessed as reduction in H2N-HK-[Nepsilon-acetyl-lysine]-LM-COOH ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50209640(CHEMBL3884812)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of recombinant human His6/GST-tagged SIRT1 expressed in Escherichia coli assessed as reduction in H2N-HK-[Nepsilon-acetyl-lysine]-LM-COOH ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50209631(CHEMBL3885246)
Affinity DataIC50:  3.93E+4nMAssay Description:Inhibition of recombinant human His6/GST-tagged SIRT1 expressed in Escherichia coli assessed as reduction in H2N-HK-[Nepsilon-acetyl-lysine]-LM-COOH ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50209636(CHEMBL3885466)
Affinity DataIC50:  4.58E+4nMAssay Description:Inhibition of recombinant human His6/GST-tagged SIRT1 expressed in Escherichia coli assessed as reduction in H2N-HK-[Nepsilon-acetyl-lysine]-LM-COOH ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50209631(CHEMBL3885246)
Affinity DataIC50:  5.42E+4nMAssay Description:Inhibition of recombinant human His6-tagged SIRT3 (101 to 399 residues) expressed in Escherichia coli assessed as inhibition of H2N-HK-[epsilonN-acet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50209630(CHEMBL3883598)
Affinity DataIC50:  5.77E+4nMAssay Description:Inhibition of recombinant human His6/GST-tagged SIRT1 expressed in Escherichia coli assessed as reduction in H2N-HK-[Nepsilon-acetyl-lysine]-LM-COOH ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50209634(CHEMBL3883514)
Affinity DataIC50:  7.75E+4nMAssay Description:Inhibition of recombinant human His6/GST-tagged SIRT1 expressed in Escherichia coli assessed as reduction in H2N-HK-[Nepsilon-acetyl-lysine]-LM-COOH ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50209647(CHEMBL3885209)
Affinity DataIC50:  1.16E+5nMAssay Description:Inhibition of recombinant human His6/GST-tagged SIRT1 expressed in Escherichia coli assessed as reduction in H2N-HK-[Nepsilon-acetyl-lysine]-LM-COOH ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50209635(CHEMBL3883946)
Affinity DataIC50:  1.33E+5nMAssay Description:Inhibition of recombinant human His6/GST-tagged SIRT1 expressed in Escherichia coli assessed as reduction in H2N-HK-[Nepsilon-acetyl-lysine]-LM-COOH ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50209646(CHEMBL3884953)
Affinity DataIC50:  1.50E+5nMAssay Description:Inhibition of recombinant human His6/GST-tagged SIRT1 expressed in Escherichia coli assessed as reduction in H2N-HK-[Nepsilon-acetyl-lysine]-LM-COOH ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50209642(CHEMBL3884070)
Affinity DataIC50:  1.71E+5nMAssay Description:Inhibition of recombinant human His6/GST-tagged SIRT1 expressed in Escherichia coli assessed as reduction in H2N-HK-[Nepsilon-acetyl-lysine]-LM-COOH ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50209650(CHEMBL3884314)
Affinity DataIC50:  1.87E+5nMAssay Description:Inhibition of recombinant human His6/GST-tagged SIRT1 expressed in Escherichia coli assessed as reduction in H2N-HK-[Nepsilon-acetyl-lysine]-LM-COOH ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50209638(CHEMBL3883974)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of recombinant human His6-tagged SIRT2 (2 to 389 residues) expressed in Escherichia coli assessed as inhibition of H2N-HK-[epsilonN-acetyl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50209632(CHEMBL3884524)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of recombinant human His6/GST-tagged SIRT1 expressed in Escherichia coli assessed as reduction in H2N-HK-[Nepsilon-acetyl-lysine]-LM-COOH ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50209648(CHEMBL3884078)
Affinity DataIC50: >9.00E+5nMAssay Description:Inhibition of recombinant human His6/GST-tagged SIRT1 expressed in Escherichia coli assessed as reduction in H2N-HK-[Nepsilon-acetyl-lysine]-LM-COOH ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-3, mitochondrial(Homo sapiens (Human))
Jiangsu University

Curated by ChEMBL
LigandPNGBDBM50209638(CHEMBL3883974)
Affinity DataIC50: >1.00E+6nMAssay Description:Inhibition of recombinant human His6-tagged SIRT3 (101 to 399 residues) expressed in Escherichia coli assessed as inhibition of H2N-HK-[epsilonN-acet...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed