TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of full-length recombinant human His-tagged BMX expressed in baculovirus expression system using Poly(4:1 Glu, Tyr) as substrate after 1 h...More data for this Ligand-Target Pair
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: 8nMAssay Description:Inhibition of full-length recombinant human His-tagged BMX expressed in baculovirus expression system using Poly(4:1 Glu, Tyr) as substrate after 1 h...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of full-length recombinant human His-tagged BTK expressed in baculovirus expression system by Z'-LYTE assayMore data for this Ligand-Target Pair
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of full-length recombinant human His-tagged BMX expressed in baculovirus expression system using Poly(4:1 Glu, Tyr) as substrate after 1 h...More data for this Ligand-Target Pair
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Inhibition of full-length recombinant human His-tagged BMX expressed in baculovirus expression system using Poly(4:1 Glu, Tyr) as substrate after 1 h...More data for this Ligand-Target Pair
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibitory activity against radioligand [3H]paroxetine binding at the serotonin transporterMore data for this Ligand-Target Pair
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: 86nMAssay Description:Inhibition of full-length recombinant human His-tagged BMX expressed in baculovirus expression system using Poly(4:1 Glu, Tyr) as substrate after 1 h...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: 89nMAssay Description:Inhibition of full-length recombinant human GST-tagged p38alpha expressed in Escherichia coli by Z'-LYTE assayMore data for this Ligand-Target Pair
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: 102nMAssay Description:Inhibition of full-length recombinant human His-tagged BMX expressed in baculovirus expression system using Poly(4:1 Glu, Tyr) as substrate after 1 h...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: 106nMAssay Description:Inhibition of full-length recombinant human GST-tagged p38alpha expressed in Escherichia coli by Z'-LYTE assayMore data for this Ligand-Target Pair
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: 120nMAssay Description:Inhibition of full-length recombinant human His-tagged BMX expressed in baculovirus expression system using Poly(4:1 Glu, Tyr) as substrate after 1 h...More data for this Ligand-Target Pair
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: 133nMAssay Description:Inhibition of full-length recombinant human His-tagged BMX expressed in baculovirus expression system using Poly(4:1 Glu, Tyr) as substrate after 1 h...More data for this Ligand-Target Pair
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: 212nMAssay Description:Inhibition of human GST-tagged DDR1 catalytic domain expressed in baculovirus expression system by LanthaScreen assayMore data for this Ligand-Target Pair
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: 225nMAssay Description:Inhibitory activity against radioligand [3H]WIN-35428 binding at the dopamine transporterMore data for this Ligand-Target Pair
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibition of full-length recombinant human His-tagged BMX expressed in baculovirus expression system using Poly(4:1 Glu, Tyr) as substrate after 1 h...More data for this Ligand-Target Pair
TargetEpithelial discoidin domain-containing receptor 1(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: 265nMAssay Description:Inhibitory activity against radioligand [3H]WIN-35428 binding at the dopamine transporterMore data for this Ligand-Target Pair
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: 279nMAssay Description:Inhibition of full-length recombinant human His-tagged BMX expressed in baculovirus expression system using Poly(4:1 Glu, Tyr) as substrate after 1 h...More data for this Ligand-Target Pair
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: 382nMAssay Description:Antagonist activity against hPR (human progesterone receptor) compared to that of progesterone (100%)More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: 437nMAssay Description:Inhibition of full-length recombinant human His-tagged BTK expressed in baculovirus expression system using Poly(4:1 Glu, Tyr) as substrate after 1 h...More data for this Ligand-Target Pair
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: 480nMAssay Description:Inhibition of full-length recombinant human His-tagged BMX expressed in baculovirus expression system using Poly(4:1 Glu, Tyr) as substrate after 1 h...More data for this Ligand-Target Pair
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: 540nMAssay Description:Inhibition of full-length recombinant human His-tagged BMX expressed in baculovirus expression system using Poly(4:1 Glu, Tyr) as substrate after 1 h...More data for this Ligand-Target Pair
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: 591nMAssay Description:Inhibition of full-length recombinant human His-tagged BMX expressed in baculovirus expression system using Poly(4:1 Glu, Tyr) as substrate after 1 h...More data for this Ligand-Target Pair
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: 637nMAssay Description:Antagonist activity against hPR (human progesterone receptor) compared to that of progesterone (100%)More data for this Ligand-Target Pair
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: 813nMAssay Description:Inhibition of full-length recombinant human His-tagged BMX expressed in baculovirus expression system using Poly(4:1 Glu, Tyr) as substrate after 1 h...More data for this Ligand-Target Pair
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: 927nMAssay Description:Inhibition of full-length recombinant human His-tagged BMX expressed in baculovirus expression system using Poly(4:1 Glu, Tyr) as substrate after 1 h...More data for this Ligand-Target Pair
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: 1.15E+3nMAssay Description:Agonist activity was determined against hPR (human progesterone receptor) compared to that of progesterone (100%)More data for this Ligand-Target Pair
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: 1.26E+3nMAssay Description:Agonist activity was determined against hPR (human progesterone receptor) compared to that of progesterone (100%)More data for this Ligand-Target Pair
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibitory activity against radioligand [3H]paroxetine binding at the serotonin transporterMore data for this Ligand-Target Pair
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibition of full-length recombinant human His-tagged BMX expressed in baculovirus expression system using Poly(4:1 Glu, Tyr) as substrate after 1 h...More data for this Ligand-Target Pair
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibition of full-length recombinant human His-tagged BMX expressed in baculovirus expression system using Poly(4:1 Glu, Tyr) as substrate after 1 h...More data for this Ligand-Target Pair
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: 2.37E+3nMAssay Description:Inhibition of full-length recombinant human His-tagged BMX expressed in baculovirus expression system using Poly(4:1 Glu, Tyr) as substrate after 1 h...More data for this Ligand-Target Pair
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: 2.38E+3nMAssay Description:Inhibitory activity against radioligand [3H]WIN-35428 binding at the dopamine transporterMore data for this Ligand-Target Pair
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: 2.43E+3nMAssay Description:Inhibition of full-length recombinant human His-tagged BMX expressed in baculovirus expression system using Poly(4:1 Glu, Tyr) as substrate after 1 h...More data for this Ligand-Target Pair
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: 2.47E+3nMAssay Description:Inhibition of full-length recombinant human His-tagged BMX expressed in baculovirus expression system using Poly(4:1 Glu, Tyr) as substrate after 1 h...More data for this Ligand-Target Pair
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: 2.56E+3nMAssay Description:Inhibitory activity against radioligand [3H]nisoxetine binding at the norepinephrine transporterMore data for this Ligand-Target Pair
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: 2.82E+3nMAssay Description:Inhibition of full-length recombinant human His-tagged BMX expressed in baculovirus expression system using Poly(4:1 Glu, Tyr) as substrate after 1 h...More data for this Ligand-Target Pair
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: 2.88E+3nMAssay Description:Compound was evaluated for inhibitory constant against CD45More data for this Ligand-Target Pair
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: 3.03E+3nMAssay Description:Agonist activity was determined against hPR (human progesterone receptor) compared to that of progesterone (100%)More data for this Ligand-Target Pair
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: 4.02E+3nMAssay Description:Inhibition of full-length recombinant human His-tagged BMX expressed in baculovirus expression system using Poly(4:1 Glu, Tyr) as substrate after 1 h...More data for this Ligand-Target Pair
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: 4.62E+3nMAssay Description:Inhibition of full-length recombinant human His-tagged BMX expressed in baculovirus expression system using Poly(4:1 Glu, Tyr) as substrate after 1 h...More data for this Ligand-Target Pair
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: 5.16E+3nMAssay Description:Inhibition of full-length recombinant human His-tagged BMX expressed in baculovirus expression system using Poly(4:1 Glu, Tyr) as substrate after 1 h...More data for this Ligand-Target Pair
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: 5.47E+3nMAssay Description:Inhibition of full-length recombinant human His-tagged BMX expressed in baculovirus expression system using Poly(4:1 Glu, Tyr) as substrate after 1 h...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Compound was evaluated for 50% inhibition of PTP1B using uM)More data for this Ligand-Target Pair
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against radioligand [3H]paroxetine binding at the serotonin transporterMore data for this Ligand-Target Pair
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of full-length recombinant human His-tagged BMX expressed in baculovirus expression system using Poly(4:1 Glu, Tyr) as substrate after 1 h...More data for this Ligand-Target Pair
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of full-length recombinant human His-tagged BMX expressed in baculovirus expression system using Poly(4:1 Glu, Tyr) as substrate after 1 h...More data for this Ligand-Target Pair
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Agonist activity was determined against hPR (human progesterone receptor) compared to that of progesterone (100%)More data for this Ligand-Target Pair
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataKd: 81nMAssay Description:Binding affinity to inactive state of full length fluorescent labeled human BMX (1 to 675 amino acid residues) expressed in bacterial expression syst...More data for this Ligand-Target Pair
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataEC50: 5.80nMAssay Description:Irreversible inhibition of inactive state of wild-type full-length recombinant His-tagged BMX phosphorylation (unknown origin) at tyrosine residue ex...More data for this Ligand-Target Pair
TargetCytoplasmic tyrosine-protein kinase BMX(Homo sapiens (Human))
High Magnetic Field Laboratory
Curated by ChEMBL
High Magnetic Field Laboratory
Curated by ChEMBL
Affinity DataEC50: 197nMAssay Description:Irreversible inhibition of inactive state of wild-type full-length recombinant His-tagged BMX phosphorylation (unknown origin) at tyrosine residue ex...More data for this Ligand-Target Pair