Compile Data Set for Download or QSAR
maximum 50k data
Found 48 Enz. Inhib. hit(s) with all data for entry = 50001425
Target72 kDa type IV collagenase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278363(CHEMBL4163839)
Affinity DataIC50:  210nMAssay Description:Inhibition of recombinant human MMP2 (Tyr110 to Asp452 residues) using Ac-Pro-Leu-Gly-S-Leu-Leu-Gly-OEt as substrate after 1 hr measured at 1 min tim...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278364(CHEMBL4160618)
Affinity DataIC50:  1.65E+3nMAssay Description:Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liver; (observed value)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278367(CHEMBL4170455)
Affinity DataIC50:  2.12E+3nMAssay Description:Inhibition of recombinant human MMP2 (Tyr110 to Asp452 residues) using Ac-Pro-Leu-Gly-S-Leu-Leu-Gly-OEt as substrate after 1 hr measured at 1 min tim...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278388(CHEMBL4171886)
Affinity DataIC50:  2.85E+3nMAssay Description:Concentration required to achieve 50% inhibition against 4-hydroxyphenylpyruvate dioxygenase from pig liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278366(CHEMBL4162521)
Affinity DataIC50:  4.07E+3nMAssay Description:Inhibition of recombinant human MMP2 (Tyr110 to Asp452 residues) using Ac-Pro-Leu-Gly-S-Leu-Leu-Gly-OEt as substrate after 1 hr measured at 1 min tim...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278390(CHEMBL4175156)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of recombinant human MMP2 (Tyr110 to Asp452 residues) using Ac-Pro-Leu-Gly-S-Leu-Leu-Gly-OEt as substrate after 1 hr measured at 1 min tim...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278389(CHEMBL4164016)
Affinity DataIC50:  4.80E+3nMAssay Description:Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liver; (observed value)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278365(CHEMBL4167291)
Affinity DataIC50:  5.14E+3nMAssay Description:Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liver; (observed value)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278389(CHEMBL4164016)
Affinity DataIC50:  5.34E+3nMAssay Description:Inhibition of recombinant human MMP2 (Tyr110 to Asp452 residues) using Ac-Pro-Leu-Gly-S-Leu-Leu-Gly-OEt as substrate after 1 hr measured at 1 min tim...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278367(CHEMBL4170455)
Affinity DataIC50:  5.97E+3nMAssay Description:Inhibition of recombinant human MMP9 (Phe107 to Pro449 residues) expressed in Escherichia coli using Ac-Pro-Leu-Gly-S-Leu-Leu-Gly-OEt as substrate af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278366(CHEMBL4162521)
Affinity DataIC50:  6.36E+3nMAssay Description:Inhibition of recombinant human MMP9 (Phe107 to Pro449 residues) expressed in Escherichia coli using Ac-Pro-Leu-Gly-S-Leu-Leu-Gly-OEt as substrate af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278363(CHEMBL4163839)
Affinity DataIC50:  6.37E+3nMAssay Description:Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liverMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278390(CHEMBL4175156)
Affinity DataIC50:  6.80E+3nMAssay Description:Inhibition of recombinant human MMP9 (Phe107 to Pro449 residues) expressed in Escherichia coli using Ac-Pro-Leu-Gly-S-Leu-Leu-Gly-OEt as substrate af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278364(CHEMBL4160618)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of recombinant human MMP9 (Phe107 to Pro449 residues) expressed in Escherichia coli using Ac-Pro-Leu-Gly-S-Leu-Leu-Gly-OEt as substrate af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278388(CHEMBL4171886)
Affinity DataIC50:  7.50E+3nMAssay Description:Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278365(CHEMBL4167291)
Affinity DataIC50:  8.52E+3nMAssay Description:Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liver; (observed value)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278364(CHEMBL4160618)
Affinity DataIC50:  7.63E+4nMAssay Description:Inhibition of recombinant human MMP14 (Tyr112 to Arg298 residues) expressed in Escherichia coli using Ac-Pro-Leu-Gly-S-Leu-Leu-Gly-OEt as substrate a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278389(CHEMBL4164016)
Affinity DataIC50:  8.71E+4nMAssay Description:Inhibition of recombinant human MMP14 (Tyr112 to Arg298 residues) expressed in Escherichia coli using Ac-Pro-Leu-Gly-S-Leu-Leu-Gly-OEt as substrate a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278363(CHEMBL4163839)
Affinity DataIC50:  9.52E+4nMAssay Description:Concentration required to achieve 50% inhibition against 4-hydroxyphenylpyruvate dioxygenase from pig liver; (observed value)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278364(CHEMBL4160618)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of recombinant human MMP12 (Phe99 to Leu271 residues) expressed in Escherichia coli using Ac-Pro-Leu-Gly-S-Leu-Leu-Gly-OEt as substrate af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278363(CHEMBL4163839)
Affinity DataIC50:  1.09E+5nMAssay Description:Inhibition of recombinant human MMP14 (Tyr112 to Arg298 residues) expressed in Escherichia coli using Ac-Pro-Leu-Gly-S-Leu-Leu-Gly-OEt as substrate a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278389(CHEMBL4164016)
Affinity DataIC50:  1.09E+5nMAssay Description:Inhibitor concentration of the compound against alpha-L-Fucosidase from Human placentaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278366(CHEMBL4162521)
Affinity DataIC50:  1.11E+5nMAssay Description:Inhibitor concentration of the compound against Beta-galactosidase from Aspergillus orizaeMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278363(CHEMBL4163839)
Affinity DataIC50:  1.73E+5nMAssay Description:Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liverMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278366(CHEMBL4162521)
Affinity DataIC50:  1.98E+5nMAssay Description:Inhibition of recombinant human MMP12 (Phe99 to Leu271 residues) expressed in Escherichia coli using Ac-Pro-Leu-Gly-S-Leu-Leu-Gly-OEt as substrate af...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278364(CHEMBL4160618)
Affinity DataIC50:  1.99E+5nMAssay Description:Inhibition of recombinant human MMP8 (Phe99 to Gln269 residues) expressed in Escherichia coli using Ac-Pro-Leu-Gly-S-Leu-Leu-Gly-OEt as substrate aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278389(CHEMBL4164016)
Affinity DataIC50:  2.99E+5nMAssay Description:Inhibition of recombinant human MMP8 (Phe99 to Gln269 residues) expressed in Escherichia coli using Ac-Pro-Leu-Gly-S-Leu-Leu-Gly-OEt as substrate aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278367(CHEMBL4170455)
Affinity DataIC50:  3.01E+5nMAssay Description:Inhibition of recombinant human MMP14 (Tyr112 to Arg298 residues) expressed in Escherichia coli using Ac-Pro-Leu-Gly-S-Leu-Leu-Gly-OEt as substrate a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278365(CHEMBL4167291)
Affinity DataIC50:  3.09E+5nMAssay Description:Inhibition of recombinant human MMP14 (Tyr112 to Arg298 residues) expressed in Escherichia coli using Ac-Pro-Leu-Gly-S-Leu-Leu-Gly-OEt as substrate a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278366(CHEMBL4162521)
Affinity DataIC50:  3.46E+5nMAssay Description:Inhibition of recombinant human MMP8 (Phe99 to Gln269 residues) expressed in Escherichia coli using Ac-Pro-Leu-Gly-S-Leu-Leu-Gly-OEt as substrate aft...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278388(CHEMBL4171886)
Affinity DataIC50:  4.01E+5nMAssay Description:Inhibition of recombinant human MMP8 (Phe99 to Gln269 residues) expressed in Escherichia coli using Ac-Pro-Leu-Gly-S-Leu-Leu-Gly-OEt as substrate aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278390(CHEMBL4175156)
Affinity DataIC50:  4.36E+5nMAssay Description:Inhibition of recombinant human MMP14 (Tyr112 to Arg298 residues) expressed in Escherichia coli using Ac-Pro-Leu-Gly-S-Leu-Leu-Gly-OEt as substrate a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278365(CHEMBL4167291)
Affinity DataIC50:  4.83E+5nMAssay Description:Inhibition of recombinant human MMP8 (Phe99 to Gln269 residues) expressed in Escherichia coli using Ac-Pro-Leu-Gly-S-Leu-Leu-Gly-OEt as substrate aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278367(CHEMBL4170455)
Affinity DataIC50:  4.93E+5nMAssay Description:Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liver; (observed value)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278390(CHEMBL4175156)
Affinity DataIC50:  4.93E+5nMAssay Description:Inhibitor concentration of the compound against alpha-L-Fucosidase from Bovine epididymis was testedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278367(CHEMBL4170455)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of recombinant human MMP1 (Phe100 to Gln268 residues) using Ac-Pro-Leu-Gly-S-Leu-Leu-Gly-OEt as substrate after 1 hr measured at 1 min tim...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278390(CHEMBL4175156)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of recombinant human MMP8 (Phe99 to Gln269 residues) expressed in Escherichia coli using Ac-Pro-Leu-Gly-S-Leu-Leu-Gly-OEt as substrate aft...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278365(CHEMBL4167291)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibitor concentration of the compound against alpha-L-Fucosidase from Human placentaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278388(CHEMBL4171886)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of recombinant human MMP14 (Tyr112 to Arg298 residues) expressed in Escherichia coli using Ac-Pro-Leu-Gly-S-Leu-Leu-Gly-OEt as substrate a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278388(CHEMBL4171886)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of recombinant human MMP12 (Phe99 to Leu271 residues) expressed in Escherichia coli using Ac-Pro-Leu-Gly-S-Leu-Leu-Gly-OEt as substrate af...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278367(CHEMBL4170455)
Affinity DataIC50: >5.00E+5nMAssay Description:Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278366(CHEMBL4162521)
Affinity DataIC50: >5.00E+5nMAssay Description:Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liver; (observed value)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278390(CHEMBL4175156)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of recombinant human MMP1 (Phe100 to Gln268 residues) using Ac-Pro-Leu-Gly-S-Leu-Leu-Gly-OEt as substrate after 1 hr measured at 1 min tim...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278365(CHEMBL4167291)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of recombinant human MMP1 (Phe100 to Gln268 residues) using Ac-Pro-Leu-Gly-S-Leu-Leu-Gly-OEt as substrate after 1 hr measured at 1 min tim...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278388(CHEMBL4171886)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of recombinant human MMP1 (Phe100 to Gln268 residues) using Ac-Pro-Leu-Gly-S-Leu-Leu-Gly-OEt as substrate after 1 hr measured at 1 min tim...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278389(CHEMBL4164016)
Affinity DataIC50: >5.00E+5nMAssay Description:Concentration required to achieve 50% inhibition against 4-Hydroxyphenylpyruvate dioxygenase (HPPD) from pig liverMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278363(CHEMBL4163839)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition constant of the compound against Beta-galactosidase from Jack beans; Mixed (Non competitive and competitive)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Jadavpur University

Curated by ChEMBL
LigandPNGBDBM50278364(CHEMBL4160618)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of recombinant human MMP1 (Phe100 to Gln268 residues) using Ac-Pro-Leu-Gly-S-Leu-Leu-Gly-OEt as substrate after 1 hr measured at 1 min tim...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed