Found 21 Enz. Inhib. hit(s) with all data for entry = 50009178 
Affinity DataIC50: <1.20nMAssay Description:Inhibition of human FGFR4 using Poly [E,Y] 4:1 substrate pre-incubated for 15 to 60 mins followed by ATP and [gamma33P]-ATP additionMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20nMAssay Description:Inhibition of N-terminal GST-tagged recombinant human FGFR1 (456 to 765 amino acids) incubated for 60 mins by time-resolved fluorescence kinase assayMore data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 2nMAssay Description:Inhibition of human FGFR1 using poly[Glu:Tyr] (4:1) substrate and ATP and [gamma33P]-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:Inhibition of human FGFR2 using poly[Glu:Tyr] (4:1) substrate and ATP and [gamma33P]-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Inhibition of human FGFR2 incubated for 30 mins by time-resolved fluorescence kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Inhibition of FGFR2 (unknown origin) using poly[Glu:Tyr] (4:1) substrate and ATP and [gamma33P]-ATP incubated for 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.80nMAssay Description:Inhibition of FGFR1 (unknown origin) using poly[Glu:Tyr] (4:1) substrate and ATP and [gamma33P]-ATP incubated for 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of N-terminal GST-fused human FGFR4 cytoplasmic domain (460 to 802(end) amino acids) using CSKtide substrate incubated for 90 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of N-terminal His6-tagged recombinant human FGFR3 (447 to 761 residues) incubated for 60 mins by time-resolved fluorescence kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.70nMAssay Description:Inhibition of human FGFR4 incubated for 45 mins by time-resolved fluorescence kinase assayMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Inhibition of FGFR4 (unknown origin) using poly[Glu:Tyr] (4:1) substrate and ATP and [gamma33P]-ATP incubated for 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 6.40nMAssay Description:Inhibition of FGFR3 (unknown origin) using poly[Glu:Tyr] (4:1) substrate and ATP and [gamma33P]-ATP incubated for 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 8nMAssay Description:Inhibition of human FGFR4 using poly[Glu:Tyr] (4:1) substrate and ATP and [gamma33P]-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 18nMAssay Description:Inhibition of human FGFR3 using poly[Glu:Tyr] (4:1) substrate and ATP and [gamma33P]-ATPMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Jinan University
Curated by ChEMBL
Jinan University
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of N-terminal GST-fused human FGFR3 cytoplasmic domain (436 to 806(end) amino acids) using CSKtide substrate incubated for 90 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 320nMAssay Description:Inhibition of human FGFR1 using KKKSPGEYVNIEFG substrate pre-incubated for 15 to 60 mins followed by ATP and [gamma33P]-ATP additionMore data for this Ligand-Target Pair
Affinity DataIC50: 493nMAssay Description:Inhibition of N-terminal GST-fused human FGFR2 cytoplasmic domain (399 to 821(end) amino acids) using CSKtide substrate incubated for 90 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 591nMAssay Description:Inhibition of N-terminal GST-fused human FGFR1 cytoplasmic domain (398 to 822(end) amino acids) using CSKtide substrate incubated for 90 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of human FGFR3 using Poly [E,Y] 4:1 substrate pre-incubated for 15 to 60 mins followed by ATP and [gamma33P]-ATP additionMore data for this Ligand-Target Pair
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of human FGFR2 using Poly [E,Y] 4:1 substrate pre-incubated for 15 to 60 mins followed by ATP and [gamma33P]-ATP additionMore data for this Ligand-Target Pair
