Compile Data Set for Download or QSAR
maximum 50k data
Found 53 Enz. Inhib. hit(s) with all data for entry = 50012255
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Institute Of Experimental Botany Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50555913(CHEMBL4750752)
Affinity DataIC50:  140nMAssay Description:Inhibition of human recombinant 5-LOX assessed as reduction in LTB4 level using 800 uM arachidonic acid as substrate preincubated with enzyme for 10 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Institute Of Experimental Botany Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50555922(CHEMBL4752615)
Affinity DataIC50:  170nMAssay Description:Inhibition of human recombinant 5-LOX assessed as reduction in LTB4 level using 800 uM arachidonic acid as substrate preincubated with enzyme for 10 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Institute Of Experimental Botany Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50531315(CHEMBL4463619)
Affinity DataIC50:  250nMAssay Description:Inhibition of ovine COX-1 assessed as reduction in PGE2 level using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mins followed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Institute Of Experimental Botany Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50555911(CHEMBL4761227)
Affinity DataIC50:  280nMAssay Description:Inhibition of human recombinant 5-LOX assessed as reduction in LTB4 level using 800 uM arachidonic acid as substrate preincubated with enzyme for 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Institute Of Experimental Botany Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50555910(CHEMBL469433)
Affinity DataIC50:  340nMAssay Description:Inhibition of human recombinant 5-LOX assessed as reduction in LTB4 level using 800 uM arachidonic acid as substrate preincubated with enzyme for 10 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institute Of Experimental Botany Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50555911(CHEMBL4761227)
Affinity DataIC50:  550nMAssay Description:Inhibition of human recombinant COX-2 assessed as reduction in PGE2 level using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institute Of Experimental Botany Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50555910(CHEMBL469433)
Affinity DataIC50:  570nMAssay Description:Inhibition of human recombinant COX-2 assessed as reduction in PGE2 level using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Institute Of Experimental Botany Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50000541((+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea |...)
Affinity DataIC50:  660nMAssay Description:Inhibition of human recombinant 5-LOX assessed as reduction in LTB4 level using 800 uM arachidonic acid as substrate preincubated with enzyme for 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Institute Of Experimental Botany Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50555910(CHEMBL469433)
Affinity DataIC50:  710nMAssay Description:Inhibition of human recombinant 5-LOX assessed as reduction in LTB4 level using 5 to 80 uM arachidonic acid as substrate preincubated with enzyme for...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Institute Of Experimental Botany Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50531316(CHEMBL4550999)
Affinity DataIC50:  790nMAssay Description:Inhibition of human recombinant 5-LOX assessed as reduction in LTB4 level using 800 uM arachidonic acid as substrate preincubated with enzyme for 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Institute Of Experimental Botany Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50555910(CHEMBL469433)
Affinity DataIC50:  800nMAssay Description:Competitive inhibition of ovine COX-1 assessed as reduction in PGE2 level using 50 nM arachidonic acid as substrate preincubated with enzyme for 5 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institute Of Experimental Botany Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50531315(CHEMBL4463619)
Affinity DataIC50:  880nMAssay Description:Inhibition of human recombinant COX-2 assessed as reduction in PGE2 level using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Institute Of Experimental Botany Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50555919(CHEMBL4783791)
Affinity DataIC50:  940nMAssay Description:Inhibition of human recombinant 5-LOX assessed as reduction in LTB4 level using 800 uM arachidonic acid as substrate preincubated with enzyme for 10 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Institute Of Experimental Botany Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50555917(CHEMBL4764453)
Affinity DataIC50:  1.01E+3nMAssay Description:Inhibition of human recombinant 5-LOX assessed as reduction in LTB4 level using 800 uM arachidonic acid as substrate preincubated with enzyme for 10 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Institute Of Experimental Botany Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50555921(CHEMBL4759223)
Affinity DataIC50:  1.02E+3nMAssay Description:Inhibition of human recombinant 5-LOX assessed as reduction in LTB4 level using 800 uM arachidonic acid as substrate preincubated with enzyme for 10 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Institute Of Experimental Botany Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50531315(CHEMBL4463619)
Affinity DataIC50:  1.05E+3nMAssay Description:Inhibition of human recombinant 5-LOX assessed as reduction in LTB4 level using 800 uM arachidonic acid as substrate preincubated with enzyme for 10 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Institute Of Experimental Botany Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50555910(CHEMBL469433)
Affinity DataIC50:  1.07E+3nMAssay Description:Inhibition of ovine COX-1 assessed as reduction in PGE2 level using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mins followed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Institute Of Experimental Botany Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50555911(CHEMBL4761227)
Affinity DataIC50:  1.07E+3nMAssay Description:Inhibition of ovine COX-1 assessed as reduction in PGE2 level using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mins followed ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Institute Of Experimental Botany Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50555920(CHEMBL4749311)
Affinity DataIC50:  1.09E+3nMAssay Description:Inhibition of human recombinant 5-LOX assessed as reduction in LTB4 level using 800 uM arachidonic acid as substrate preincubated with enzyme for 10 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Institute Of Experimental Botany Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50555915(CHEMBL4742702)
Affinity DataIC50:  1.14E+3nMAssay Description:Inhibition of human recombinant 5-LOX assessed as reduction in LTB4 level using 800 uM arachidonic acid as substrate preincubated with enzyme for 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Institute Of Experimental Botany Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50555909(CHEBI:8413 | Primin)
Affinity DataIC50:  1.37E+3nMAssay Description:Inhibition of human recombinant 5-LOX assessed as reduction in LTB4 level using 800 uM arachidonic acid as substrate preincubated with enzyme for 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Institute Of Experimental Botany Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50555912(CHEMBL4798135)
Affinity DataIC50:  1.49E+3nMAssay Description:Inhibition of human recombinant 5-LOX assessed as reduction in LTB4 level using 800 uM arachidonic acid as substrate preincubated with enzyme for 10 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institute Of Experimental Botany Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50555912(CHEMBL4798135)
Affinity DataIC50:  1.55E+3nMAssay Description:Inhibition of human recombinant COX-2 assessed as reduction in PGE2 level using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Institute Of Experimental Botany Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50555916(CHEMBL4781249)
Affinity DataIC50:  1.67E+3nMAssay Description:Inhibition of human recombinant 5-LOX assessed as reduction in LTB4 level using 800 uM arachidonic acid as substrate preincubated with enzyme for 10 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institute Of Experimental Botany Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50555909(CHEBI:8413 | Primin)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of human recombinant COX-2 assessed as reduction in PGE2 level using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institute Of Experimental Botany Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50555908(3-Pentadecylresorcinol | 5-Pentadecylresorcinol | ...)
Affinity DataIC50:  2.36E+3nMAssay Description:Inhibition of human recombinant COX-2 assessed as reduction in PGE2 level using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Institute Of Experimental Botany Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50259933(5-tridecyl resorcinol | 6-tridecylresorcylic acid ...)
Affinity DataIC50:  2.38E+3nMAssay Description:Inhibition of ovine COX-1 assessed as reduction in PGE2 level using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mins followed ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institute Of Experimental Botany Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50169047((S)-2-(4-Isobutyl-phenyl)-propionic acid | (S)-2-(...)
Affinity DataIC50:  2.46E+3nMAssay Description:Inhibition of human recombinant COX-2 assessed as reduction in PGE2 level using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mi...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Institute Of Experimental Botany Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50555913(CHEMBL4750752)
Affinity DataIC50:  2.65E+3nMAssay Description:Inhibition of ovine COX-1 assessed as reduction in PGE2 level using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mins followed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institute Of Experimental Botany Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50555913(CHEMBL4750752)
Affinity DataIC50:  2.71E+3nMAssay Description:Inhibition of human recombinant COX-2 assessed as reduction in PGE2 level using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institute Of Experimental Botany Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50259933(5-tridecyl resorcinol | 6-tridecylresorcylic acid ...)
Affinity DataIC50:  2.74E+3nMAssay Description:Inhibition of human recombinant COX-2 assessed as reduction in PGE2 level using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Institute Of Experimental Botany Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50555910(CHEMBL469433)
Affinity DataIC50:  2.77E+3nMAssay Description:Competitive inhibition of ovine COX-1 assessed as reduction in PGE2 level using 250 nM arachidonic acid as substrate preincubated with enzyme for 5 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Institute Of Experimental Botany Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50555912(CHEMBL4798135)
Affinity DataIC50:  3.38E+3nMAssay Description:Inhibition of ovine COX-1 assessed as reduction in PGE2 level using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mins followed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
Institute Of Experimental Botany Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50555914(CHEMBL4739960)
Affinity DataIC50:  3.72E+3nMAssay Description:Inhibition of human recombinant 5-LOX assessed as reduction in LTB4 level using 800 uM arachidonic acid as substrate preincubated with enzyme for 10 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institute Of Experimental Botany Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50555916(CHEMBL4781249)
Affinity DataIC50:  4.48E+3nMAssay Description:Inhibition of human recombinant COX-2 assessed as reduction in PGE2 level using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Institute Of Experimental Botany Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50169047((S)-2-(4-Isobutyl-phenyl)-propionic acid | (S)-2-(...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of ovine COX-1 assessed as reduction in PGE2 level using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mins followed ...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institute Of Experimental Botany Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50555914(CHEMBL4739960)
Affinity DataIC50:  4.65E+3nMAssay Description:Inhibition of human recombinant COX-2 assessed as reduction in PGE2 level using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institute Of Experimental Botany Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50555915(CHEMBL4742702)
Affinity DataIC50:  4.81E+3nMAssay Description:Inhibition of human recombinant COX-2 assessed as reduction in PGE2 level using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Institute Of Experimental Botany Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50169047((S)-2-(4-Isobutyl-phenyl)-propionic acid | (S)-2-(...)
Affinity DataIC50:  4.96E+3nMAssay Description:Competitive inhibition of ovine COX-1 assessed as reduction in PGE2 level using 50 nM arachidonic acid as substrate preincubated with enzyme for 5 mi...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Institute Of Experimental Botany Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50555914(CHEMBL4739960)
Affinity DataIC50:  5.42E+3nMAssay Description:Inhibition of ovine COX-1 assessed as reduction in PGE2 level using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mins followed ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Institute Of Experimental Botany Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50555908(3-Pentadecylresorcinol | 5-Pentadecylresorcinol | ...)
Affinity DataIC50:  5.61E+3nMAssay Description:Inhibition of ovine COX-1 assessed as reduction in PGE2 level using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mins followed ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institute Of Experimental Botany Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50555917(CHEMBL4764453)
Affinity DataIC50:  5.82E+3nMAssay Description:Inhibition of human recombinant COX-2 assessed as reduction in PGE2 level using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Institute Of Experimental Botany Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50555915(CHEMBL4742702)
Affinity DataIC50:  6.11E+3nMAssay Description:Inhibition of ovine COX-1 assessed as reduction in PGE2 level using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mins followed ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institute Of Experimental Botany Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50531316(CHEMBL4550999)
Affinity DataIC50:  8.97E+3nMAssay Description:Inhibition of human recombinant COX-2 assessed as reduction in PGE2 level using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Institute Of Experimental Botany Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50555907(CHEBI:66960 | While Olivetol)
Affinity DataIC50:  1.36E+4nMAssay Description:Inhibition of ovine COX-1 assessed as reduction in PGE2 level using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mins followed ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Institute Of Experimental Botany Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50555916(CHEMBL4781249)
Affinity DataIC50:  1.56E+4nMAssay Description:Inhibition of ovine COX-1 assessed as reduction in PGE2 level using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mins followed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Institute Of Experimental Botany Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50555917(CHEMBL4764453)
Affinity DataIC50:  1.58E+4nMAssay Description:Inhibition of ovine COX-1 assessed as reduction in PGE2 level using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mins followed ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institute Of Experimental Botany Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50555918(CHEMBL503824)
Affinity DataIC50:  1.59E+4nMAssay Description:Inhibition of human recombinant COX-2 assessed as reduction in PGE2 level using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Institute Of Experimental Botany Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50169047((S)-2-(4-Isobutyl-phenyl)-propionic acid | (S)-2-(...)
Affinity DataIC50:  1.62E+4nMAssay Description:Competitive inhibition of ovine COX-1 assessed as reduction in PGE2 level using 250 nM arachidonic acid as substrate preincubated with enzyme for 5 m...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Institute Of Experimental Botany Of The Czech Academy Of Sciences

Curated by ChEMBL
LigandPNGBDBM50555907(CHEBI:66960 | While Olivetol)
Affinity DataIC50:  1.73E+4nMAssay Description:Inhibition of human recombinant COX-2 assessed as reduction in PGE2 level using 10 uM arachidonic acid as substrate preincubated with enzyme for 5 mi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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