Found 26 Enz. Inhib. hit(s) with all data for entry = 50012050 
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of recombinant CYP2C8 (unknown origin)More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Bristol Myers Squibb
Curated by ChEMBL
Bristol Myers Squibb
Curated by ChEMBL
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of recombinant CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of recombinant CYP2D6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of recombinant CYP2C19 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of recombinant CYP2C9 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of recombinant CYP1A2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 18nMAssay Description:Inverse agonist activity at RORgammat in CD3 and CD28-stimulated human whole blood assessed as reduction in IL17A production incubated for 1 hr befor...More data for this Ligand-Target Pair
Affinity DataEC50: 13nMAssay Description:Inverse agonist activity at RORgammat in CD3 and CD28-stimulated human whole blood assessed as reduction in IL17A production incubated for 1 hr befor...More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataEC50: 24nMAssay Description:Inverse agonist activity at RORgammat in CD3 and CD28-stimulated human whole blood assessed as reduction in IL17A production incubated for 1 hr befor...More data for this Ligand-Target Pair
Affinity DataEC50: 52nMAssay Description:Inverse agonist activity at RORgammat in CD3 and CD28-stimulated human whole blood assessed as reduction in IL17A production incubated for 1 hr befor...More data for this Ligand-Target Pair
Affinity DataEC50: 30nMAssay Description:Inverse agonist activity at RORgammat in CD3 and CD28-stimulated human whole blood assessed as reduction in IL17A production incubated for 1 hr befor...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of GAL4-fused RORalpha (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+4nMAssay Description:Inhibition of GAL4-fused RORbeta (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 2nMAssay Description:Inverse agonist activity at RORgammat in mouse Th17 cellsMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Bristol Myers Squibb
Curated by ChEMBL
Bristol Myers Squibb
Curated by ChEMBL
Affinity DataEC50: 9.20E+3nMAssay Description:Inverse agonist activity of PXR (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: >1.20E+4nMAssay Description:Inverse agonist activity of LXRalpha (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: >7.50E+3nMAssay Description:Inverse agonist activity of LXRbeta (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 40nMAssay Description:Inverse agonist activity at RORgammat in CD3 and CD28-stimulated human whole blood assessed as reduction in IL17A production incubated for 1 hr befor...More data for this Ligand-Target Pair
Affinity DataEC50: 33nMAssay Description:Inverse agonist activity at RORgammat in CD3 and CD28-stimulated human whole blood assessed as reduction in IL17A production incubated for 1 hr befor...More data for this Ligand-Target Pair
Affinity DataEC50: 17nMAssay Description:Inverse agonist activity at Gal4-fused RORgammat (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 9.60nMAssay Description:Inverse agonist activity at Gal4-fused RORgammat (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 2.80nMAssay Description:Inverse agonist activity at Gal4-fused RORgammat (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 3.20nMAssay Description:Inverse agonist activity at Gal4-fused RORgammat (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 3.30E+3nMAssay Description:Inverse agonist activity at Gal4-fused RORgammat (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 870nMAssay Description:Inverse agonist activity at Gal4-fused RORgammat (unknown origin)More data for this Ligand-Target Pair
