BindingDB PrimarySearch_ki

Found 42 Enz. Inhib. hit(s) with all data for entry = 50012913

cAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL

PNG

BDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)

IC50: 110nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged PDE4D3 expressed in baculovirus infected Sf9 cells by radioligand binding assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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3D Structure (crystal)

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL

PNG

BDBM14361((R,S)-Rolipram | 4-(3-cyclopentyloxy-4-methoxy-phe...)

IC50: 110nMAssay Description:Inhibition of recombinant human C-terminal His-tagged N-terminal GST-tagged PDE4B2 expressed in baculovirus infected Sf9 cells by radioligand binding...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

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CHEMBL MCE
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3D Structure (crystal)

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL

PNG

BDBM50561535(CHEMBL4762079)

IC50: 110nMAssay Description:Inhibition of recombinant human C-terminal His-tagged N-terminal GST-tagged PDE4B2 expressed in baculovirus infected Sf9 cells by radioligand binding...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL

PNG

BDBM50561537(CHEMBL4783529)

IC50: 140nMAssay Description:Inhibition of recombinant human C-terminal His-tagged N-terminal GST-tagged PDE4B2 expressed in baculovirus infected Sf9 cells by radioligand binding...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL

PNG

BDBM50561545(CHEMBL4763078)

IC50: 210nMAssay Description:Inhibition of recombinant human C-terminal His-tagged N-terminal GST-tagged PDE4B2 expressed in baculovirus infected Sf9 cells by radioligand binding...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL

PNG

BDBM50561536(CHEMBL4781035)

IC50: 230nMAssay Description:Inhibition of recombinant human C-terminal His-tagged N-terminal GST-tagged PDE4B2 expressed in baculovirus infected Sf9 cells by radioligand binding...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL

PNG

BDBM50561556(CHEMBL4793481)

IC50: 410nMAssay Description:Inhibition of recombinant human C-terminal His-tagged N-terminal GST-tagged PDE4B2 expressed in baculovirus infected Sf9 cells by radioligand binding...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL

PNG

BDBM50561538(CHEMBL4759907)

IC50: 430nMAssay Description:Inhibition of recombinant human C-terminal His-tagged N-terminal GST-tagged PDE4B2 expressed in baculovirus infected Sf9 cells by radioligand binding...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL

PNG

BDBM50561548(CHEMBL4754568)

IC50: 430nMAssay Description:Inhibition of recombinant human C-terminal His-tagged N-terminal GST-tagged PDE4B2 expressed in baculovirus infected Sf9 cells by radioligand binding...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL

PNG

BDBM50561535(CHEMBL4762079)

IC50: 450nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged PDE4D3 expressed in baculovirus infected Sf9 cells by radioligand binding assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL

PNG

BDBM50561532(CHEMBL4789557)

IC50: 480nMAssay Description:Inhibition of recombinant human C-terminal His-tagged N-terminal GST-tagged PDE4B2 expressed in baculovirus infected Sf9 cells by radioligand binding...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL

PNG

BDBM50561554(CHEMBL4786383)

IC50: 490nMAssay Description:Inhibition of recombinant human C-terminal His-tagged N-terminal GST-tagged PDE4B2 expressed in baculovirus infected Sf9 cells by radioligand binding...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL

PNG

BDBM50561534(CHEMBL4765220)

IC50: 600nMAssay Description:Inhibition of recombinant human C-terminal His-tagged N-terminal GST-tagged PDE4B2 expressed in baculovirus infected Sf9 cells by radioligand binding...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL

PNG

BDBM50561553(CHEMBL4758800)

IC50: 610nMAssay Description:Inhibition of recombinant human C-terminal His-tagged N-terminal GST-tagged PDE4B2 expressed in baculovirus infected Sf9 cells by radioligand binding...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL

PNG

BDBM355750(N-Cyclopropyl-3-(3,4-dichlorophenyl)-3H-imidazo[4,...)

IC50: 630nMAssay Description:Inhibition of recombinant human C-terminal His-tagged N-terminal GST-tagged PDE4B2 expressed in baculovirus infected Sf9 cells by radioligand binding...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL

PNG

BDBM355756(3-(3-Chloro-4-methylphenyl)-N-cyclopropyl-3H-imida...)

IC50: 800nMAssay Description:Inhibition of recombinant human C-terminal His-tagged N-terminal GST-tagged PDE4B2 expressed in baculovirus infected Sf9 cells by radioligand binding...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL

PNG

BDBM50561537(CHEMBL4783529)

IC50: 880nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged PDE4D3 expressed in baculovirus infected Sf9 cells by radioligand binding assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL

PNG

BDBM50561542(CHEMBL4797566)

IC50: 910nMAssay Description:Inhibition of recombinant human C-terminal His-tagged N-terminal GST-tagged PDE4B2 expressed in baculovirus infected Sf9 cells by radioligand binding...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL

PNG

BDBM50561551(CHEMBL4795799)

IC50: 970nMAssay Description:Inhibition of recombinant human C-terminal His-tagged N-terminal GST-tagged PDE4B2 expressed in baculovirus infected Sf9 cells by radioligand binding...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL

PNG

BDBM50561539(CHEMBL4786718)

IC50: 980nMAssay Description:Inhibition of recombinant human C-terminal His-tagged N-terminal GST-tagged PDE4B2 expressed in baculovirus infected Sf9 cells by radioligand binding...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL

PNG

BDBM50561555(CHEMBL4758348)

IC50: 980nMAssay Description:Inhibition of recombinant human C-terminal His-tagged N-terminal GST-tagged PDE4B2 expressed in baculovirus infected Sf9 cells by radioligand binding...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL

PNG

BDBM50561538(CHEMBL4759907)

IC50: 1.00E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged PDE4D3 expressed in baculovirus infected Sf9 cells by radioligand binding assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL

PNG

BDBM50561533(CHEMBL4763816)

IC50: 1.10E+3nMAssay Description:Inhibition of recombinant human C-terminal His-tagged N-terminal GST-tagged PDE4B2 expressed in baculovirus infected Sf9 cells by radioligand binding...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL

PNG

BDBM50561544(CHEMBL4798020)

IC50: 1.30E+3nMAssay Description:Inhibition of recombinant human C-terminal His-tagged N-terminal GST-tagged PDE4B2 expressed in baculovirus infected Sf9 cells by radioligand binding...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL

PNG

BDBM50561552(CHEMBL4763514)

IC50: 1.30E+3nMAssay Description:Inhibition of recombinant human C-terminal His-tagged N-terminal GST-tagged PDE4B2 expressed in baculovirus infected Sf9 cells by radioligand binding...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL

PNG

BDBM50561543(CHEMBL4751002)

IC50: 1.40E+3nMAssay Description:Inhibition of recombinant human C-terminal His-tagged N-terminal GST-tagged PDE4B2 expressed in baculovirus infected Sf9 cells by radioligand binding...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL

PNG

BDBM50561546(CHEMBL4779670)

IC50: 1.40E+3nMAssay Description:Inhibition of recombinant human C-terminal His-tagged N-terminal GST-tagged PDE4B2 expressed in baculovirus infected Sf9 cells by radioligand binding...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL

PNG

BDBM50561554(CHEMBL4786383)

IC50: 1.60E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged PDE4D3 expressed in baculovirus infected Sf9 cells by radioligand binding assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL

PNG

BDBM50561547(CHEMBL4754846)

IC50: 1.80E+3nMAssay Description:Inhibition of recombinant human C-terminal His-tagged N-terminal GST-tagged PDE4B2 expressed in baculovirus infected Sf9 cells by radioligand binding...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL

PNG

BDBM50561555(CHEMBL4758348)

IC50: 1.90E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged PDE4D3 expressed in baculovirus infected Sf9 cells by radioligand binding assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL

PNG

BDBM50561531(CHEMBL4761224)

IC50: 2.00E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged PDE4D3 expressed in baculovirus infected Sf9 cells by radioligand binding assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL

PNG

BDBM50561539(CHEMBL4786718)

IC50: 2.30E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged PDE4D3 expressed in baculovirus infected Sf9 cells by radioligand binding assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL

PNG

BDBM50561540(CHEMBL4790633)

IC50: 2.30E+3nMAssay Description:Inhibition of recombinant human C-terminal His-tagged N-terminal GST-tagged PDE4B2 expressed in baculovirus infected Sf9 cells by radioligand binding...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL

PNG

BDBM50561531(CHEMBL4761224)

IC50: 2.40E+3nMAssay Description:Inhibition of recombinant human C-terminal His-tagged N-terminal GST-tagged PDE4B2 expressed in baculovirus infected Sf9 cells by radioligand binding...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL

PNG

BDBM50561549(CHEMBL4745467)

IC50: 2.90E+3nMAssay Description:Inhibition of recombinant human C-terminal His-tagged N-terminal GST-tagged PDE4B2 expressed in baculovirus infected Sf9 cells by radioligand binding...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL

PNG

BDBM50561530(CHEMBL4752210)

IC50: 4.20E+3nMAssay Description:Inhibition of recombinant human C-terminal His-tagged N-terminal GST-tagged PDE4B2 expressed in baculovirus infected Sf9 cells by radioligand binding...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL

PNG

BDBM50561550(CHEMBL4757647)

IC50: 5.00E+3nMAssay Description:Inhibition of recombinant human C-terminal His-tagged N-terminal GST-tagged PDE4B2 expressed in baculovirus infected Sf9 cells by radioligand binding...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL

PNG

BDBM50561556(CHEMBL4793481)

IC50: 6.30E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged PDE4D3 expressed in baculovirus infected Sf9 cells by radioligand binding assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Sigma intracellular receptor 2(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL

PNG

BDBM50561537(CHEMBL4783529)

IC50: 7.80E+3nMAssay Description:Inhibition of sigma2 receptor (unknown origin)More data for this Ligand-Target Pair

UniProtKB/SwissProt
GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL

PNG

BDBM355756(3-(3-Chloro-4-methylphenyl)-N-cyclopropyl-3H-imida...)

IC50: 8.20E+3nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged PDE4D3 expressed in baculovirus infected Sf9 cells by radioligand binding assayMore data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

cAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL

PNG

BDBM50561541(CHEMBL4764438)

IC50: 9.40E+3nMAssay Description:Inhibition of recombinant human C-terminal His-tagged N-terminal GST-tagged PDE4B2 expressed in baculovirus infected Sf9 cells by radioligand binding...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

Details Article PubMed

5-hydroxytryptamine receptor 2C(Homo sapiens (Human))
University Of Nebraska Medical Center

Curated by ChEMBL

PNG

BDBM50561537(CHEMBL4783529)

IC50: >1.00E+4nMAssay Description:Inhibition of 5HT2C (unknown origin)More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Details Article PubMed