Compile Data Set for Download or QSAR
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Found 26 Enz. Inhib. hit(s) with all data for entry = 50013463
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50185114(2-(2-chlorobenzamido)-4,5,6,7-tetrahydrobenzo[b]th...)
Affinity DataEC50:  326nMAssay Description:Potentiation of CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells co-expressing YFP incubated for 10 mins by halide potentiator ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50566257(CHEMBL4785210)
Affinity DataEC50: >3.00E+4nMAssay Description:Inhibition of human ERG by manual patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50566249(CHEMBL4795314)
Affinity DataEC50:  13nMAssay Description:Potentiation of CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells co-expressing YFP incubated for 10 mins by halide potentiator ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50566250(CHEMBL4784536)
Affinity DataEC50:  29nMAssay Description:Potentiation of CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells co-expressing YFP incubated for 10 mins by halide potentiator ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50566251(CHEMBL4776744)
Affinity DataEC50:  352nMAssay Description:Potentiation of CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells co-expressing YFP incubated for 10 mins by halide potentiator ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50566252(CHEMBL4777140)
Affinity DataEC50:  79nMAssay Description:Potentiation of CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells co-expressing YFP incubated for 10 mins by halide potentiator ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50566253(CHEMBL4782437)
Affinity DataEC50:  26nMAssay Description:Potentiation of CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells co-expressing YFP incubated for 10 mins by halide potentiator ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50566254(CHEMBL4781656)
Affinity DataEC50:  20nMAssay Description:Potentiation of CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells co-expressing YFP incubated for 10 mins by halide potentiator ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50566255(CHEMBL4793801)
Affinity DataEC50:  33nMAssay Description:Potentiation of CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells co-expressing YFP incubated for 10 mins by halide potentiator ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50566256(CHEMBL4798183)
Affinity DataEC50:  3.40nMAssay Description:Potentiation of CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells co-expressing YFP incubated for 10 mins by halide potentiator ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50566257(CHEMBL4785210)
Affinity DataEC50:  11nMAssay Description:Potentiation of CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells co-expressing YFP incubated for 10 mins by halide potentiator ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50566258(CHEMBL4787310)
Affinity DataEC50:  2.80nMAssay Description:Potentiation of CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells co-expressing YFP incubated for 10 mins by halide potentiator ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50566259(CHEMBL4795705)
Affinity DataEC50:  7.80nMAssay Description:Potentiation of CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells co-expressing YFP incubated for 10 mins by halide potentiator ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50566260(CHEMBL4787733)
Affinity DataEC50: >2.00E+3nMAssay Description:Potentiation of CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells co-expressing YFP incubated for 10 mins by halide potentiator ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50566261(CHEMBL4789045)
Affinity DataEC50: >2.00E+3nMAssay Description:Potentiation of CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells co-expressing YFP incubated for 10 mins by halide potentiator ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50566262(CHEMBL4799994)
Affinity DataEC50:  1.10nMAssay Description:Potentiation of CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells co-expressing YFP incubated for 10 mins by halide potentiator ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50566263(CHEMBL4776653)
Affinity DataEC50: <0.310nMAssay Description:Potentiation of CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells co-expressing YFP incubated for 10 mins by halide potentiator ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50566264(CHEMBL4781857)
Affinity DataEC50:  5nMAssay Description:Potentiation of CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells co-expressing YFP incubated for 10 mins by halide potentiator ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50566254(CHEMBL4781656)
Affinity DataEC50:  478nMAssay Description:Potentiation of CFTR G551D mutant (unknown origin) expressed in human HEK293 cells co-expressing YFP incubated for 10 mins by halide potentiator assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50566257(CHEMBL4785210)
Affinity DataEC50:  18nMAssay Description:Potentiation of CFTR F508del mutant in human HBE cells by trans-epithelial clamp circuit assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50566257(CHEMBL4785210)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50566257(CHEMBL4785210)
Affinity DataEC50: >3.30E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50566257(CHEMBL4785210)
Affinity DataEC50:  2.60E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50566257(CHEMBL4785210)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50566257(CHEMBL4785210)
Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCystic fibrosis transmembrane conductance regulator(Homo sapiens (Human))
Galapagos

Curated by ChEMBL
LigandPNGBDBM50566248(CHEMBL4790007)
Affinity DataEC50:  17nMAssay Description:Potentiation of CFTR F508del mutant (unknown origin) expressed in human CFBE41o- cells co-expressing YFP incubated for 10 mins by halide potentiator ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed