Compile Data Set for Download or QSAR
maximum 50k data
Found 41 Enz. Inhib. hit(s) with all data for entry = 50015910
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50139171(Dinaciclib | MK-7965 | SCH-727965 | US11643396, Ex...)
Affinity DataIC50: <3nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50139171(Dinaciclib | MK-7965 | SCH-727965 | US11643396, Ex...)
Affinity DataIC50: <3nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
West China Hospital

Curated by ChEMBL
LigandPNGBDBM7478(2-chloro-4-[(2-{[(1R)-1-(hydroxymethyl)-2-methylpr...)
Affinity DataIC50:  6nMAssay Description:Inhibition of recombinant CDK2/CycA (unknown origin)More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
West China Hospital

Curated by ChEMBL
LigandPNGBDBM7478(2-chloro-4-[(2-{[(1R)-1-(hydroxymethyl)-2-methylpr...)
Affinity DataIC50:  6nMAssay Description:Inhibition of recombinant CDK5/p35 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 13(Homo sapiens (Human))
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50590457(CHEMBL5193291)
Affinity DataIC50:  10nMAssay Description:Irreversible inhibition of CDK13 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50367737(CHEMBL4173631)
Affinity DataIC50:  10nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 13(Homo sapiens (Human))
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50590457(CHEMBL5193291)
Affinity DataIC50:  10nMAssay Description:Inhibition of CDK13 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50139171(Dinaciclib | MK-7965 | SCH-727965 | US11643396, Ex...)
Affinity DataIC50:  12nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
West China Hospital

Curated by ChEMBL
LigandPNGBDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)
Affinity DataIC50:  30nMAssay Description:Inhibition of recombinant CDK1/CycB1 (unknown origin) using CTD as substrate incubated for 60 mins by Beckman scintillation counter analysisMore data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetCyclin-dependent kinase 7(Homo sapiens (Human))
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50139171(Dinaciclib | MK-7965 | SCH-727965 | US11643396, Ex...)
Affinity DataIC50:  42nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 12(Homo sapiens)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50590464(CHEMBL5179701)
Affinity DataIC50:  44nMAssay Description:Inhibition of CDK12 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCasein kinase I isoform delta(Homo sapiens (Human))
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50454220(CHEMBL4211454)
Affinity DataIC50:  44nMAssay Description:Inhibition of CK1 delta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 12(Homo sapiens)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50139171(Dinaciclib | MK-7965 | SCH-727965 | US11643396, Ex...)
Affinity DataIC50:  50nMAssay Description:Inhibition of CDK12 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 12(Homo sapiens)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50590457(CHEMBL5193291)
Affinity DataIC50:  52nMAssay Description:Inhibition of CDK12 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 12(Homo sapiens)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50590461(CHEMBL5174472)
Affinity DataIC50:  59nMAssay Description:Inhibition of CDK12 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 12(Homo sapiens)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50590459(CHEMBL5178679)
Affinity DataIC50:  63nMAssay Description:Inhibition of CDK12 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
West China Hospital

Curated by ChEMBL
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)
Affinity DataIC50:  70nMAssay Description:Inhibition of recombinant CDK2/CycA (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
West China Hospital

Curated by ChEMBL
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)
Affinity DataIC50:  75nMAssay Description:Inhibition of recombinant CDK5/p35 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 12(Homo sapiens)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50454220(CHEMBL4211454)
Affinity DataIC50:  86nMAssay Description:Inhibition of CDK12 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
West China Hospital

Curated by ChEMBL
LigandPNGBDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)
Affinity DataIC50:  100nMAssay Description:Inhibition of recombinant CDK4/CycD1 (unknown origin) using CTD as substrate incubated for 60 mins by Beckman scintillation counter analysisMore data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetCyclin-dependent kinase 12(Homo sapiens)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50298225(CHEMBL2069955 | CHEMBL573578 | NM-PP1 | US10544104...)
Affinity DataIC50:  100nMAssay Description:Inhibition of CDK12 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 12(Homo sapiens)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50540077(CHEMBL4649135)
Affinity DataIC50:  103nMAssay Description:Inhibition of CDK12 (unknown origin) in presence of high ATPMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 12(Homo sapiens)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50590458(CHEMBL5202653)
Affinity DataIC50:  130nMAssay Description:Inhibition of CDK12 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Homo sapiens (Human))
West China Hospital

Curated by ChEMBL
LigandPNGBDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)
Affinity DataIC50:  144nMAssay Description:Inhibition of recombinant CDK9/CycT1 (unknown origin) using CTD as substrate incubated for 60 mins by Beckman scintillation counter analysisMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 12(Homo sapiens)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50590462(CHEMBL5187567)
Affinity DataIC50:  250nMAssay Description:Inhibition of CDK12 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50454220(CHEMBL4211454)
Affinity DataIC50:  260nMAssay Description:Inhibition of CK1 epsilon (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 12(Homo sapiens)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50590463(CHEMBL5205448)
Affinity DataIC50:  310nMAssay Description:Inhibition of CDK12 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 12(Homo sapiens)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50367737(CHEMBL4173631)
Affinity DataIC50:  360nMAssay Description:Inhibition of CDK12 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50590458(CHEMBL5202653)
Affinity DataIC50:  470nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 12(Homo sapiens)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50590456(CHEMBL5188909)
Affinity DataIC50:  491nMAssay Description:Inhibition of CDK12 (unknown origin) in presence of high ATPMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 12(Homo sapiens)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50590460(CHEMBL5205330)
Affinity DataIC50:  750nMAssay Description:Inhibition of CDK12 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCyclin-dependent kinase 4/G1/S-specific cyclin-D1(Homo sapiens (Human))
West China Hospital

Curated by ChEMBL
LigandPNGBDBM27216((2R)-2-({6-[(3-chlorophenyl)amino]-9-(propan-2-yl)...)
Affinity DataIC50:  850nMAssay Description:Inhibition of recombinant CDK4/CycD1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 12(Homo sapiens)
West China Hospital

Curated by ChEMBL
LigandPNGBDBM5655(2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydr...)
Affinity DataIC50:  1.37E+3nMAssay Description:Inhibition of recombinant CDK12/CycK (unknown origin) using CTD as substrate incubated for 60 mins by Beckman scintillation counter analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50590456(CHEMBL5188909)
Affinity DataIC50:  2.68E+3nMAssay Description:Inhibition of CDK2 (unknown origin) in presence of high ATPMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50590456(CHEMBL5188909)
Affinity DataIC50:  9.09E+3nMAssay Description:Inhibition of CDK9 (unknown origin) in presence of high ATPMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50590457(CHEMBL5193291)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CDK7 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 8(Homo sapiens (Human))
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50590457(CHEMBL5193291)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CDK8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 9(Homo sapiens (Human))
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50590457(CHEMBL5193291)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of CDK9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 7(Homo sapiens (Human))
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50590456(CHEMBL5188909)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CDK7 (unknown origin) in presence of high ATPMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50590456(CHEMBL5188909)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of CDK1 (unknown origin) in presence of high ATPMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
West China Hospital

Curated by ChEMBL
LigandPNGBDBM50590457(CHEMBL5193291)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed