Compile Data Set for Download or QSAR
maximum 50k data
Found 66 Enz. Inhib. hit(s) with all data for entry = 209
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM228128((e)-n-(4-((3-chloro-2,4-difluorophenyl)amino)-7-me...)
Affinity DataIC50:  0.900nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
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TargetEpidermal growth factor receptor(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM228125((e)-n-(4-((3,4-dichloro-2-fluorophenyl)amino)-7-et...)
Affinity DataIC50:  1.20nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
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TargetEpidermal growth factor receptor(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM228126((e)-n-(4-((3,4-dichloro-2-fluorophenyl)amino)-7-(2...)
Affinity DataIC50:  1.5nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
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TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM228121((e)-n-(7-ethoxy-4-((1-(3-fluorobenzyl)-1h-indazol-...)
Affinity DataIC50:  1.60nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
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TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM228119((e)-n-(4-((1-(3-fluorobenzyl)-1h-indazol-5-yl)amin...)
Affinity DataIC50:  1.60nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
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TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM228117((e)-n-(4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)...)
Affinity DataIC50:  1.70nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
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TargetEpidermal growth factor receptor(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM228111((e)-n-(4-((3-chloro-4-fluorophenyl)amino)-7-(2-met...)
Affinity DataIC50:  1.80nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
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TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM228116((e)-n-(4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)...)
Affinity DataIC50:  1.80nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
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TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM228115((e)-n-(4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)...)
Affinity DataIC50:  1.90nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
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TargetEpidermal growth factor receptor(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM228124((e)-n-(4-((3,4-dichloro-2-fluorophenyl)amino)-7-me...)
Affinity DataIC50:  2.10nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
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TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM228120((e)-n-(4-((1-(3-fluorobenzyl)-1h-indazol-5-yl)amin...)
Affinity DataIC50:  2.20nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
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TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM228118((e)-n-(4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)...)
Affinity DataIC50:  2.5nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
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TargetEpidermal growth factor receptor(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM228107( (E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-metho...)
Affinity DataIC50:  3.20nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM228127((e)-n-(4-((3,4-dichloro-2-fluorophenyl)amino)-7-((...)
Affinity DataIC50:  3.30nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
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TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM228114((e)-n-(4-((3-chloro-4-((3-fluorobenzyl)oxy)phenyl)...)
Affinity DataIC50:  3.5nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
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TargetEpidermal growth factor receptor(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM228110((e)-n-(4-((3-chloro-4-fluorophenyl)amino)-7-(((s)-...)
Affinity DataIC50:  3.60nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
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TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM228122((e)-n-(4-((3-chloro-4-((3-fluorobenzyl)oxy)phenyl)...)
Affinity DataIC50:  3.70nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
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TargetEpidermal growth factor receptor [T790M](Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM228125((e)-n-(4-((3,4-dichloro-2-fluorophenyl)amino)-7-et...)
Affinity DataIC50:  4nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
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TargetEpidermal growth factor receptor [T790M](Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM228117((e)-n-(4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)...)
Affinity DataIC50:  4.20nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
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TargetEpidermal growth factor receptor(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM228108((e)-n-(4-((3-chloro-4-fluorophenyl)amino)-7-methox...)
Affinity DataIC50:  4.30nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
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TargetEpidermal growth factor receptor(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM228113((e)-n-(4-((3-chloro-4-fluorophenyl)amino)-7-(metho...)
Affinity DataIC50:  4.80nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor [T790M](Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM228126((e)-n-(4-((3,4-dichloro-2-fluorophenyl)amino)-7-(2...)
Affinity DataIC50:  5nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
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TargetEpidermal growth factor receptor [T790M](Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM228118((e)-n-(4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)...)
Affinity DataIC50:  5.90nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
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TargetEpidermal growth factor receptor [T790M](Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM228109((e)-n-(4-((3-chloro-4-fluorophenyl)amino)-7-ethoxy...)
Affinity DataIC50:  6.20nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
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TargetEpidermal growth factor receptor(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM228109((e)-n-(4-((3-chloro-4-fluorophenyl)amino)-7-ethoxy...)
Affinity DataIC50:  6.40nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
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TargetEpidermal growth factor receptor [T790M](Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM228124((e)-n-(4-((3,4-dichloro-2-fluorophenyl)amino)-7-me...)
Affinity DataIC50:  6.40nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
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TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM228123((e)-n-(4-((3-chloro-4-((3-fluorobenzyl)oxy)phenyl)...)
Affinity DataIC50:  6.60nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
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TargetEpidermal growth factor receptor [T790M](Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM228110((e)-n-(4-((3-chloro-4-fluorophenyl)amino)-7-(((s)-...)
Affinity DataIC50:  6.80nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
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TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM228125((e)-n-(4-((3,4-dichloro-2-fluorophenyl)amino)-7-et...)
Affinity DataIC50:  7nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
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TargetEpidermal growth factor receptor [T790M](Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM228127((e)-n-(4-((3,4-dichloro-2-fluorophenyl)amino)-7-((...)
Affinity DataIC50:  7nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
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TargetEpidermal growth factor receptor(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM228120((e)-n-(4-((1-(3-fluorobenzyl)-1h-indazol-5-yl)amin...)
Affinity DataIC50:  7.90nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
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TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM228109((e)-n-(4-((3-chloro-4-fluorophenyl)amino)-7-ethoxy...)
Affinity DataIC50:  8.10nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
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TargetEpidermal growth factor receptor [T790M](Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM228107( (E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-metho...)
Affinity DataIC50:  8.30nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor [T790M](Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM228116((e)-n-(4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)...)
Affinity DataIC50:  8.5nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
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TargetEpidermal growth factor receptor(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM228118((e)-n-(4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)...)
Affinity DataIC50:  8.60nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
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TargetEpidermal growth factor receptor [T790M](Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM228111((e)-n-(4-((3-chloro-4-fluorophenyl)amino)-7-(2-met...)
Affinity DataIC50:  8.70nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
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TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM228124((e)-n-(4-((3,4-dichloro-2-fluorophenyl)amino)-7-me...)
Affinity DataIC50:  9.10nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
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TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM228126((e)-n-(4-((3,4-dichloro-2-fluorophenyl)amino)-7-(2...)
Affinity DataIC50:  9.60nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
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TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM228111((e)-n-(4-((3-chloro-4-fluorophenyl)amino)-7-(2-met...)
Affinity DataIC50:  10.4nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
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TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM228110((e)-n-(4-((3-chloro-4-fluorophenyl)amino)-7-(((s)-...)
Affinity DataIC50:  11.7nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
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TargetEpidermal growth factor receptor [T790M](Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM228113((e)-n-(4-((3-chloro-4-fluorophenyl)amino)-7-(metho...)
Affinity DataIC50:  12.5nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM228107( (E)-N-(4-((3-Chloro-4-fluorophenyl)amino)-7-metho...)
Affinity DataIC50:  14nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM228119((e)-n-(4-((1-(3-fluorobenzyl)-1h-indazol-5-yl)amin...)
Affinity DataIC50:  14nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
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TargetEpidermal growth factor receptor [T790M](Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM228121((e)-n-(7-ethoxy-4-((1-(3-fluorobenzyl)-1h-indazol-...)
Affinity DataIC50:  14.5nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
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TargetEpidermal growth factor receptor(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM228114((e)-n-(4-((3-chloro-4-((3-fluorobenzyl)oxy)phenyl)...)
Affinity DataIC50:  15nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
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In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM228112((e)-n-(4-((3-chloro-4-fluorophenyl)amino)-7-(2,2,2...)
Affinity DataIC50:  15.4nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM228113((e)-n-(4-((3-chloro-4-fluorophenyl)amino)-7-(metho...)
Affinity DataIC50:  15.8nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEpidermal growth factor receptor [T790M](Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM228108((e)-n-(4-((3-chloro-4-fluorophenyl)amino)-7-methox...)
Affinity DataIC50:  16nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM228128((e)-n-(4-((3-chloro-2,4-difluorophenyl)amino)-7-me...)
Affinity DataIC50:  17.8nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Sunshine Lake Pharma

US Patent
LigandPNGBDBM228117((e)-n-(4-((3-chloro-4-(pyridin-2-ylmethoxy)phenyl)...)
Affinity DataIC50:  18.4nMpH: 7.5 T: 2°CAssay Description:Materials used include HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid), Brij-35 (dodecyl polyglycol ether), DTT (dithiothreitol), EDTA (et...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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