Compile Data Set for Download or QSAR
maximum 50k data
Found 30 Enz. Inhib. hit(s) with all data for entry = 2133
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kadmon

US Patent
LigandPNGBDBM322158(2-(3-(4-((1H-indazol-5-yl)amino)-6-(4-methylpipera...)
Affinity DataKi:  10nMAssay Description:Kinase inhibition can be determined using an IMAP® assay (Molecular Devices). This assay method involves the use of a fluorescently-tagged peptide su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon

US Patent
LigandPNGBDBM322158(2-(3-(4-((1H-indazol-5-yl)amino)-6-(4-methylpipera...)
Affinity DataKi:  20nMAssay Description:Kinase inhibition can be determined using an IMAP® assay (Molecular Devices). This assay method involves the use of a fluorescently-tagged peptide su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon

US Patent
LigandPNGBDBM322152((R)-2-(3-(4-((1H-indazol-5-yl)amino)pyrimidin-2-yl...)
Affinity DataKi:  20nMAssay Description:Kinase inhibition can be determined using an IMAP® assay (Molecular Devices). This assay method involves the use of a fluorescently-tagged peptide su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon

US Patent
LigandPNGBDBM322153(2-(3-(4-((1H-indazol-5-yl)amino)-5-methylpyrimidin...)
Affinity DataKi:  30nMAssay Description:Kinase inhibition can be determined using an IMAP® assay (Molecular Devices). This assay method involves the use of a fluorescently-tagged peptide su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon

US Patent
LigandPNGBDBM322155(US10183931, SLx-2119 | US10696660, SLx-2119 | US11...)
Affinity DataKi:  40nMAssay Description:Kinase inhibition can be determined using an IMAP® assay (Molecular Devices). This assay method involves the use of a fluorescently-tagged peptide su...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kadmon

US Patent
LigandPNGBDBM355727(US9815820, Y-27263)
Affinity DataKi:  40nMAssay Description:Kinase inhibition can be determined using an IMAP® assay (Molecular Devices). This assay method involves the use of a fluorescently-tagged peptide su...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon

US Patent
LigandPNGBDBM355727(US9815820, Y-27263)
Affinity DataKi:  60nMAssay Description:Kinase inhibition can be determined using an IMAP® assay (Molecular Devices). This assay method involves the use of a fluorescently-tagged peptide su...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kadmon

US Patent
LigandPNGBDBM322152((R)-2-(3-(4-((1H-indazol-5-yl)amino)pyrimidin-2-yl...)
Affinity DataKi:  70nMAssay Description:Kinase inhibition can be determined using an IMAP® assay (Molecular Devices). This assay method involves the use of a fluorescently-tagged peptide su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon

US Patent
LigandPNGBDBM322154(2-(3-(4-((1H-indazol-5-yl)amino)-5-methylpyrimidin...)
Affinity DataKi:  80nMAssay Description:Kinase inhibition can be determined using an IMAP® assay (Molecular Devices). This assay method involves the use of a fluorescently-tagged peptide su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon

US Patent
LigandPNGBDBM322157(2-(3-(4-((1H-indazol-5-yl)amino)pyrimidin-2-yl)phe...)
Affinity DataKi:  170nMAssay Description:Kinase inhibition can be determined using an IMAP® assay (Molecular Devices). This assay method involves the use of a fluorescently-tagged peptide su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon

US Patent
LigandPNGBDBM322152((R)-2-(3-(4-((1H-indazol-5-yl)amino)pyrimidin-2-yl...)
Affinity DataKi:  180nMAssay Description:Kinase inhibition can be determined using an IMAP® assay (Molecular Devices). This assay method involves the use of a fluorescently-tagged peptide su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kadmon

US Patent
LigandPNGBDBM322154(2-(3-(4-((1H-indazol-5-yl)amino)-5-methylpyrimidin...)
Affinity DataKi:  260nMAssay Description:Kinase inhibition can be determined using an IMAP® assay (Molecular Devices). This assay method involves the use of a fluorescently-tagged peptide su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kadmon

US Patent
LigandPNGBDBM322155(US10183931, SLx-2119 | US10696660, SLx-2119 | US11...)
Affinity DataKi:  500nMAssay Description:Kinase inhibition can be determined using an IMAP® assay (Molecular Devices). This assay method involves the use of a fluorescently-tagged peptide su...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kadmon

US Patent
LigandPNGBDBM322152((R)-2-(3-(4-((1H-indazol-5-yl)amino)pyrimidin-2-yl...)
Affinity DataKi:  870nMAssay Description:Kinase inhibition can be determined using an IMAP® assay (Molecular Devices). This assay method involves the use of a fluorescently-tagged peptide su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kadmon

US Patent
LigandPNGBDBM322153(2-(3-(4-((1H-indazol-5-yl)amino)-5-methylpyrimidin...)
Affinity DataKi:  2.01E+3nMAssay Description:Kinase inhibition can be determined using an IMAP® assay (Molecular Devices). This assay method involves the use of a fluorescently-tagged peptide su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kadmon

US Patent
LigandPNGBDBM322158(2-(3-(4-((1H-indazol-5-yl)amino)-6-(4-methylpipera...)
Affinity DataIC50:  330nMAssay Description:Kinase inhibition can be determined using an IMAP® assay (Molecular Devices). This assay method involves the use of a fluorescently-tagged peptide su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon

US Patent
LigandPNGBDBM322158(2-(3-(4-((1H-indazol-5-yl)amino)-6-(4-methylpipera...)
Affinity DataIC50:  470nMAssay Description:Kinase inhibition can be determined using an IMAP® assay (Molecular Devices). This assay method involves the use of a fluorescently-tagged peptide su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon

US Patent
LigandPNGBDBM322152((R)-2-(3-(4-((1H-indazol-5-yl)amino)pyrimidin-2-yl...)
Affinity DataIC50:  540nMAssay Description:Kinase inhibition can be determined using an IMAP® assay (Molecular Devices). This assay method involves the use of a fluorescently-tagged peptide su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon

US Patent
LigandPNGBDBM322153(2-(3-(4-((1H-indazol-5-yl)amino)-5-methylpyrimidin...)
Affinity DataIC50:  720nMAssay Description:Kinase inhibition can be determined using an IMAP® assay (Molecular Devices). This assay method involves the use of a fluorescently-tagged peptide su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon

US Patent
LigandPNGBDBM322155(US10183931, SLx-2119 | US10696660, SLx-2119 | US11...)
Affinity DataIC50:  1.02E+3nMAssay Description:Kinase inhibition can be determined using an IMAP® assay (Molecular Devices). This assay method involves the use of a fluorescently-tagged peptide su...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kadmon

US Patent
LigandPNGBDBM355727(US9815820, Y-27263)
Affinity DataIC50:  1.13E+3nMAssay Description:Kinase inhibition can be determined using an IMAP® assay (Molecular Devices). This assay method involves the use of a fluorescently-tagged peptide su...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon

US Patent
LigandPNGBDBM355727(US9815820, Y-27263)
Affinity DataIC50:  1.63E+3nMAssay Description:Kinase inhibition can be determined using an IMAP® assay (Molecular Devices). This assay method involves the use of a fluorescently-tagged peptide su...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kadmon

US Patent
LigandPNGBDBM322152((R)-2-(3-(4-((1H-indazol-5-yl)amino)pyrimidin-2-yl...)
Affinity DataIC50:  1.77E+3nMAssay Description:Kinase inhibition can be determined using an IMAP® assay (Molecular Devices). This assay method involves the use of a fluorescently-tagged peptide su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon

US Patent
LigandPNGBDBM322154(2-(3-(4-((1H-indazol-5-yl)amino)-5-methylpyrimidin...)
Affinity DataIC50:  1.96E+3nMAssay Description:Kinase inhibition can be determined using an IMAP® assay (Molecular Devices). This assay method involves the use of a fluorescently-tagged peptide su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon

US Patent
LigandPNGBDBM322157(2-(3-(4-((1H-indazol-5-yl)amino)pyrimidin-2-yl)phe...)
Affinity DataIC50:  4.25E+3nMAssay Description:Kinase inhibition can be determined using an IMAP® assay (Molecular Devices). This assay method involves the use of a fluorescently-tagged peptide su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Kadmon

US Patent
LigandPNGBDBM322152((R)-2-(3-(4-((1H-indazol-5-yl)amino)pyrimidin-2-yl...)
Affinity DataIC50:  4.64E+3nMAssay Description:Kinase inhibition can be determined using an IMAP® assay (Molecular Devices). This assay method involves the use of a fluorescently-tagged peptide su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kadmon

US Patent
LigandPNGBDBM322154(2-(3-(4-((1H-indazol-5-yl)amino)-5-methylpyrimidin...)
Affinity DataIC50:  6.69E+3nMAssay Description:Kinase inhibition can be determined using an IMAP® assay (Molecular Devices). This assay method involves the use of a fluorescently-tagged peptide su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kadmon

US Patent
LigandPNGBDBM322155(US10183931, SLx-2119 | US10696660, SLx-2119 | US11...)
Affinity DataIC50:  1.31E+4nMAssay Description:Kinase inhibition can be determined using an IMAP® assay (Molecular Devices). This assay method involves the use of a fluorescently-tagged peptide su...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kadmon

US Patent
LigandPNGBDBM322152((R)-2-(3-(4-((1H-indazol-5-yl)amino)pyrimidin-2-yl...)
Affinity DataIC50:  2.25E+4nMAssay Description:Kinase inhibition can be determined using an IMAP® assay (Molecular Devices). This assay method involves the use of a fluorescently-tagged peptide su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Kadmon

US Patent
LigandPNGBDBM322153(2-(3-(4-((1H-indazol-5-yl)amino)-5-methylpyrimidin...)
Affinity DataIC50:  5.35E+4nMAssay Description:Kinase inhibition can be determined using an IMAP® assay (Molecular Devices). This assay method involves the use of a fluorescently-tagged peptide su...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent