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Target
Fascin
Ligand
BDBM350119
Substrate
n/a
Meas. Tech.
Chemical Library Screens and Analysis
IC50
4000±n/a nM
Citation
 Huang, X; Shue, CY Methods for inhibiting fascin US Patent  US10208043 Publication Date 2/19/2019 
Target
Name:
Fascin
Synonyms:
55 kDa actin-bundling protein | FAN1 | FSCN1 | FSCN1_HUMAN | HSN | SNL | Singed-like protein | p55
Type:
Enzyme Catalytic Domain
Mol. Mass.:
54533.89
Organism:
Homo sapiens (human)
Description:
n/a
Residue:
493
Sequence:
MTANGTAEAVQIQFGLINCGNKYLTAEAFGFKVNASASSLKKKQIWTLEQPPDEAGSAAVCLRSHLGRYLAADKDGNVTCEREVPGPDCRFLIVAHDDGRWSLQSEAHRRYFGGTEDRLSCFAQTVSPAEKWSVHIAMHPQVNIYSVTRKRYAHLSARPADEIAVDRDVPWGVDSLITLAFQDQRYSVQTADHRFLRHDGRLVARPEPATGYTLEFRSGKVAFRDCEGRYLAPSGPSGTLKAGKATKVGKDELFALEQSCAQVVLQAANERNVSTRQGMDLSANQDEETDQETFQLEIDRDTKKCAFRTHTGKYWTLTATGGVQSTASSKNASCYFDIEWRDRRITLRASNGKFVTSKKNGQLAASVETAGDSELFLMKLINRPIIVFRGEHGFIGCRKVTGTLDANRSSYDVFQLEFNDGAYNIKDSTGKYWTVGSDSAVTSSGDTPVDFFFEFCDYNKVAIKVGGRYLKGDHAGVLKASAETVDPASLWEY
  
Inhibitor
Name:
BDBM350119
Synonyms:
N-(benzo[d]thiazol-2- yl)cinnamamide | US10208043, # 20 | US10941146, # 20
Type:
Small organic molecule
Emp. Form.:
C16H12N2OS
Mol. Mass.:
280.344
SMILES:
O=C(Nc1nc2ccccc2s1)\C=C\c1ccccc1
Structure:
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