Reaction Details Report a problem with these data
Target
Sphingosine 1-phosphate receptor 3
Ligand
BDBM31349
Substrate
n/a
Meas. Tech.
Dose Response Assay for S1P3 Antagonists
IC50
>16600±n/a nM
Citation
 PubChem, PC Dose Response Assay for S1P3 Antagonists PubChem Bioassay (2007)[AID] 
Target
Name:
Sphingosine 1-phosphate receptor 3
Synonyms:
C9orf108 | C9orf47 | EDG3 | Endothelial differentiation G-protein coupled receptor 3 | S1P receptor 3 | S1P receptor Edg-3 | S1P3 | S1PR3 | S1PR3_HUMAN | Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor 3 (S1P3) | Sphingosine 1-phosphate receptor Edg-3
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42278.13
Organism:
Homo sapiens (Human)
Description:
Q99500
Residue:
378
Sequence:
MATALPPRLQPVRGNETLREHYQYVGKLAGRLKEASEGSTLTTVLFLVICSFIVLENLMVLIAIWKNNKFHNRMYFFIGNLALCDLLAGIAYKVNILMSGKKTFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDANKRHRVFLLIGMCWLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFLVKSSSRKVANHNNSERSMALLRTVVIVVSVFIACWSPLFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRLVCNCLVRGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTAPSSCIMDKNAALQNGIFCN
  
Inhibitor
Name:
BDBM31349
Synonyms:
3-(2-ethylanilino)-2-(2-furanylmethyl)-3H-isoindol-1-one | 3-(2-ethylanilino)-2-(2-furfuryl)isoindolin-1-one | 3-(2-ethylanilino)-2-(furan-2-ylmethyl)-3H-isoindol-1-one | 3-[(2-ethylphenyl)amino]-2-(furan-2-ylmethyl)-3H-isoindol-1-one | MLS000116909 | SMR000093863 | cid_5307823
Type:
Small organic molecule
Emp. Form.:
C21H20N2O2
Mol. Mass.:
332.3957
SMILES:
CCc1ccccc1NC1N(Cc2ccco2)C(=O)c2ccccc12
Structure:
Search PDB for entries with ligand similarity: