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Target
fMet-Leu-Phe receptor
Ligand
BDBM37629
Substrate
n/a
Meas. Tech.
Dose Response Assay for Formylpeptide Receptor (FPR) Ligands and Dose Response Counter-Screen Assay for Formylpeptide-Like-1 (FPRL1) Ligands
Ki
19400±n/a nM
Citation
 PubChem, PC Dose Response Assay for Formylpeptide Receptor (FPR) Ligands and Dose Response Counter-Screen Assay for Formylpeptide-Like-1 (FPRL1) Ligands PubChem Bioassay (2007)[AID] 
Target
Name:
fMet-Leu-Phe receptor
Synonyms:
FPR | FPR1 | FPR1_HUMAN | Formyl peptide Receptor | N-formyl peptide receptor 1 | N-formylpeptide chemoattractant receptor | fMLP receptor | fMet-Leu-Phe receptor | formyl peptide receptor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
38456.14
Organism:
Human
Description:
gi_4503779
Residue:
350
Sequence:
METNSSLPTNISGGTPAVSAGYLFLDIITYLVFAVTFVLGVLGNGLVIWVAGFRMTHTVTTISYLNLAVADFCFTSTLPFFMVRKAMGGHWPFGWFLCKFVFTIVDINLFGSVFLIALIALDRCVCVLHPVWTQNHRTVSLAKKVIIGPWVMALLLTLPVIIRVTTVPGKTGTVACTFNFSPWTNDPKERINVAVAMLTVRGIIRFIIGFSAPMSIVAVSYGLIATKIHKQGLIKSSRPLRVLSFVAAAFFLCWSPYQVVALIATVRIRELLQGMYKEIGIAVDVTSALAFFNSCLNPMLYVFMGQDFRERLIHALPASLERALTEDSTQTSDTATNSTLPSAEVELQAK
  
Inhibitor
Name:
BDBM37629
Synonyms:
(4E)-5-(1,3-benzodioxol-5-yl)-1-(3-methoxypropyl)-4-[oxidanyl(phenyl)methylidene]pyrrolidine-2,3-dione | (4E)-5-(1,3-benzodioxol-5-yl)-4-[hydroxy(phenyl)methylene]-1-(3-methoxypropyl)pyrrolidine-2,3-quinone | (4E)-5-(1,3-benzodioxol-5-yl)-4-[hydroxy(phenyl)methylidene]-1-(3-methoxypropyl)pyrrolidine-2,3-dione | 5-Benzo[1,3]dioxol-5-yl-4-benzoyl-3-hydroxy-1-(3-methoxy-propyl)-1,5-dihydro-pyrrol-2-one | MLS000029490 | SMR000011270 | cid_5766372
Type:
Small organic molecule
Emp. Form.:
C22H21NO6
Mol. Mass.:
395.4052
SMILES:
COCCCN1C(C(C(=O)c2ccccc2)C(=O)C1=O)c1ccc2OCOc2c1
Structure:
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