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Target
Mevalonate kinase
Ligand
BDBM31693
Substrate
n/a
Meas. Tech.
Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - MK Dose Response
IC50
>9999000±n/a nM
Citation
 PubChem, PC Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - MK Dose Response PubChem Bioassay (2007)[AID] 
Target
Name:
Mevalonate kinase
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31420.64
Organism:
Streptococcus pneumoniae D39
Description:
A0A0H2ZQX9
Residue:
292
Sequence:
MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVPAESPWRLYEEDTLSMAVYASLEYLNITEACIRCEIDSAIPEKRGMGSSAAISIAAIRAVFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDLSAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEIAISQKDAEGLGQILSQAHLHLKEIGVSSLEADSLVETALSHGALGAKMSGGGLGGCIIALVTNLTHAQELAERLEEKGAVQTWIESL
  
Inhibitor
Name:
BDBM31693
Synonyms:
4-[(2,5-Diethoxy-phenylcarbamoyl)-methyl]-piperazine-1-carboxylic acid ethyl ester | 4-[2-(2,5-diethoxyanilino)-2-keto-ethyl]piperazine-1-carboxylic acid ethyl ester;hydrochloride | 4-[2-(2,5-diethoxyanilino)-2-oxoethyl]-1-piperazinecarboxylic acid ethyl ester;hydrochloride | MLS000076321 | SMR000000824 | cid_6603397 | ethyl 4-[2-(2,5-diethoxyanilino)-2-oxoethyl]piperazine-1-carboxylate;hydrochloride | ethyl 4-[2-[(2,5-diethoxyphenyl)amino]-2-oxidanylidene-ethyl]piperazine-1-carboxylate;hydrochloride
Type:
Small organic molecule
Emp. Form.:
C19H29N3O5
Mol. Mass.:
379.4507
SMILES:
CCOC(=O)N1CCN(CC(=O)Nc2cc(OCC)ccc2OCC)CC1
Structure:
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