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Target
Mevalonate kinase
Ligand
BDBM38709
Substrate
n/a
Meas. Tech.
Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - MK Dose Response
IC50
100824.5±n/a nM
Citation
 PubChem, PC Screening for Inhibitors of the Mevalonate Pathway in Streptococcus Pneumoniae - MK Dose Response PubChem Bioassay (2007)[AID] 
Target
Name:
Mevalonate kinase
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31420.64
Organism:
Streptococcus pneumoniae D39
Description:
A0A0H2ZQX9
Residue:
292
Sequence:
MTKKVGVGQAHSKIILIGEHAVVYGYPAISLPLLEVEVTCKVVPAESPWRLYEEDTLSMAVYASLEYLNITEACIRCEIDSAIPEKRGMGSSAAISIAAIRAVFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDLSAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEIAISQKDAEGLGQILSQAHLHLKEIGVSSLEADSLVETALSHGALGAKMSGGGLGGCIIALVTNLTHAQELAERLEEKGAVQTWIESL
  
Inhibitor
Name:
BDBM38709
Synonyms:
2-[4-(4-phenylbenzyl)piperazino]pyrimidine | 2-[4-[(4-phenylphenyl)methyl]-1-piperazinyl]pyrimidine | 2-[4-[(4-phenylphenyl)methyl]piperazin-1-yl]pyrimidine | MLS000105352 | SMR000102233 | cid_764664
Type:
Small organic molecule
Emp. Form.:
C21H22N4
Mol. Mass.:
330.4262
SMILES:
C(N1CCN(CC1)c1ncccn1)c1ccc(cc1)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: