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Target
Isoform 2 of Nuclear receptor ROR-alpha (Alpha-2)
Ligand
BDBM38961
Substrate
n/a
Meas. Tech.
Dose-response cell-based assay for inhibitors of the Retinoic Acid Receptor-related orphan receptor A (RORA)
IC50
308±n/a nM
Citation
 PubChem, PC Dose-response cell-based assay for inhibitors of the Retinoic Acid Receptor-related orphan receptor A (RORA) PubChem Bioassay (2007)[AID] 
Target
Name:
Isoform 2 of Nuclear receptor ROR-alpha (Alpha-2)
Synonyms:
NR1F1 | Nuclear receptor ROR-alpha | Nuclear receptor ROR-alpha (Alpha-2) | Nuclear receptor ROR-alpha (Retinoid-related orphan receptor-alpha) (Nuclear receptor RZR-alpha). | RORA | RORA_HUMAN | RZRA
Type:
PROTEIN
Mol. Mass.:
63033.59
Organism:
Homo sapiens (Human)
Description:
EBI_101591
Residue:
556
Sequence:
MNEGAPGDSDLETEARVPWSIMGHCLRTGQARMSATPTPAGEGARRDELFGILQILHQCILSSGDAFVLTGVCCSWRQNGKPPYSQKEDKEVQTGYMNAQIEIIPCKICGDKSSGIHYGVITCEGCKGFFRRSQQSNATYSCPRQKNCLIDRTSRNRCQHCRLQKCLAVGMSRDAVKFGRMSKKQRDSLYAEVQKHRMQQQQRDHQQQPGEAEPLTPTYNISANGLTELHDDLSNYIDGHTPEGSKADSAVSSFYLDIQPSPDQSGLDINGIKPEPICDYTPASGFFPYCSFTNGETSPTVSMAELEHLAQNISKSHLETCQYLREELQQITWQTFLQEEIENYQNKQREVMWQLCAIKITEAIQYVVEFAKRIDGFMELCQNDQIVLLKAGSLEVVFIRMCRAFDSQNNTVYFDGKYASPDVFKSLGCEDFISFVFEFGKSLCSMHLTEDEIALFSAFVLMSADRSWLQEKVKIEKLQQKIQLALQHVLQKNHREDGILTKLICKVSTLRALCGRHTEKLMAFKAIYPDIVRLHFPPLYKELFTSEFEPAMQIDG
  
Inhibitor
Name:
BDBM38961
Synonyms:
2-(4-methyl-1-piperidinyl)-1,3-benzothiazole-6-carboxylic acid | 2-(4-methylpiperidin-1-yl)-1,3-benzothiazole-6-carboxylic acid | 2-(4-methylpiperidino)-1,3-benzothiazole-6-carboxylic acid | MLS000093675 | SMR000029293 | cid_3238343
Type:
Small organic molecule
Emp. Form.:
C14H16N2O2S
Mol. Mass.:
276.354
SMILES:
CC1CCN(CC1)c1nc2ccc(cc2s1)C(O)=O
Structure:
Search PDB for entries with ligand similarity: