Reaction Details Report a problem with these data
Target
Dual specificity protein phosphatase 1
Ligand
BDBM31042
Substrate
n/a
Meas. Tech.
Cdc25B Catalytic Domain Protein Tyrosine Phosphatase Probe Assessment: MKP-1 Dose Response Selectivity comparison.
IC50
>50000±n/a nM
Citation
 PubChem, PC Cdc25B Catalytic Domain Protein Tyrosine Phosphatase Probe Assessment: MKP-1 Dose Response Selectivity comparison. PubChem Bioassay (2007)[AID] 
Target
Name:
Dual specificity protein phosphatase 1
Synonyms:
CL100 | DUS1_HUMAN | DUSP1 | Dual specificity protein phosphatase hVH1 | MAP kinase phosphatase 1 | MKP-1 | MKP1 | PTPN10 | Protein-tyrosine phosphatase CL100 | VH1
Type:
Protein phosphatase
Mol. Mass.:
39301.48
Organism:
Homo sapiens (Human)
Description:
gi_4758204
Residue:
367
Sequence:
MVMEVGTLDAGGLRALLGERAAQCLLLDCRSFFAFNAGHIAGSVNVRFSTIVRRRAKGAMGLEHIVPNAELRGRLLAGAYHAVVLLDERSAALDGAKRDGTLALAAGALCREARAAQVFFLKGGYEAFSASCPELCSKQSTPMGLSLPLSTSVPDSAESGCSSCSTPLYDQGGPVEILPFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHYQYKSIPVEDNHKADISSWFNEAIDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNRVKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQVLAPHCSAEAGSPAMAVLDRGTSTTTVFNFPVSIPVHSTNSALSYLQSPITTSPSC
  
Inhibitor
Name:
BDBM31042
Synonyms:
(5-acetamido-4-acetyloxy-2,1,3-benzoxadiazol-7-yl) acetate | (5-acetamido-4-acetyloxy-2,1,3-benzoxadiazol-7-yl) ethanoate | Acetic acid 7-acetoxy-5-acetylamino-benzo[1,2,5]oxadiazol-4-yl ester | MLS000077136 | SMR000008576 | acetic acid (5-acetamido-4-acetyloxy-2,1,3-benzoxadiazol-7-yl) ester | acetic acid (6-acetamido-7-acetoxy-benzofurazan-4-yl) ester | cid_597363
Type:
Small organic molecule
Emp. Form.:
C12H11N3O6
Mol. Mass.:
293.2322
SMILES:
CC(=O)Nc1cc(OC(C)=O)c2nonc2c1OC(C)=O
Structure:
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