Reaction Details Report a problem with these data
Target
POsterior Segregation
Ligand
BDBM52861
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA
EC50
300000±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA PubChem Bioassay (2009)[AID] 
Target
Name:
POsterior Segregation
Synonyms:
POsterior Segregation family member (pos-1)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29838.90
Organism:
Caenorhabditis elegans
Description:
gi_17562800
Residue:
264
Sequence:
MADNDFLSGEAIMVFKKEILDSHSDFTRSLSHQSASPEAYDQENVFSQDFQPFMKQDKETQNSASQPTSEQSLANRDPCTVPDDLREEMMRQRRKEDAFKTALCDAYKRSQACSYGDQCRFAHGVHELRLPMNPRGRNHPKYKTVLCDKFSMTGNCKYGTRCQFIHKIVDGNAAKLASGAHANTSSKSPARNAAAHNHSLFVPQGSTDRSMDLNQSLPIRQSDLVRAFARATRLDVSGYNSTAQLAQYFESQFQRIQQLSSHHH
  
Inhibitor
Name:
BDBM52861
Synonyms:
2-Cyano-2-[(1,3-dimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)-hydrazono]-acetamide | 2-amino-N-[(1,3-dimethyl-2,6-dioxo-7H-purin-8-yl)amino]-2-oxoethanimidoyl cyanide | 2-cyano-2-[(1,3-dimethyl-2,6-dioxo-7H-purin-8-yl)hydrazinylidene]acetamide | 2-cyano-2-[(2,6-diketo-1,3-dimethyl-7H-purin-8-yl)hydrazono]acetamide | 2-cyano-2-[[1,3-dimethyl-2,6-bis(oxidanylidene)-7H-purin-8-yl]hydrazinylidene]ethanamide | MLS001049402 | SMR000426814 | cid_1900431
Type:
Small organic molecule
Emp. Form.:
C10H10N8O3
Mol. Mass.:
290.2382
SMILES:
Cn1c2nc(NN=C(C#N)C(N)=O)[nH]c2c(=O)n(C)c1=O |w:6.5|
Structure:
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