Reaction Details Report a problem with these data
Target
Streptokinase A
Ligand
BDBM54843
Substrate
n/a
Meas. Tech.
Absorbance Microorganism-Based Dose Response Followup to Identify Inhibitors of Streptokinase Expression
EC50
3652±1220 nM
Citation
 PubChem, PC Absorbance Microorganism-Based Dose Response Followup to Identify Inhibitors of Streptokinase Expression PubChem Bioassay (2009)[AID] 
Target
Name:
Streptokinase A
Synonyms:
STRP_STRP1 | ska | streptokinase A precursor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49924.80
Organism:
Streptococcus pyogenes M1 GAS
Description:
gi_15675770
Residue:
440
Sequence:
MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVFINFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQAKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGYTIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKYYVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEERKAYSYLRDTGTPIPDNPKDK
  
Inhibitor
Name:
BDBM54843
Synonyms:
5-(2,3-dihydro-1,4-benzodioxin-3-ylmethylsulfamoyl)-2-fluoranyl-N-(4-propan-2-ylphenyl)benzamide | 5-(2,3-dihydro-1,4-benzodioxin-3-ylmethylsulfamoyl)-2-fluoro-N-(4-propan-2-ylphenyl)benzamide | 5-(2,3-dihydro-1,4-benzodioxin-3-ylmethylsulfamoyl)-2-fluoro-N-p-cumenyl-benzamide | BRD-A01217170-001-04-2 | cid_4605161
Type:
Small organic molecule
Emp. Form.:
C25H25FN2O5S
Mol. Mass.:
484.54
SMILES:
CC(C)c1ccc(NC(=O)c2cc(ccc2F)S(=O)(=O)NCC2COc3ccccc3O2)cc1
Structure:
Search PDB for entries with ligand similarity: