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Target
Streptokinase A
Ligand
BDBM54846
Substrate
n/a
Meas. Tech.
Absorbance Microorganism-Based Dose Response Followup to Identify Inhibitors of Streptokinase Expression
EC50
7089±1308 nM
Citation
 PubChem, PC Absorbance Microorganism-Based Dose Response Followup to Identify Inhibitors of Streptokinase Expression PubChem Bioassay (2009)[AID] 
Target
Name:
Streptokinase A
Synonyms:
STRP_STRP1 | ska | streptokinase A precursor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49924.80
Organism:
Streptococcus pyogenes M1 GAS
Description:
gi_15675770
Residue:
440
Sequence:
MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVFINFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQAKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGYTIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKYYVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEERKAYSYLRDTGTPIPDNPKDK
  
Inhibitor
Name:
BDBM54846
Synonyms:
2,5-dimethyl-3-furancarboxylic acid [2-oxo-1-phenyl-2-[3-(trifluoromethyl)anilino]ethyl] ester | 2,5-dimethylfuran-3-carboxylic acid [2-keto-1-phenyl-2-[3-(trifluoromethyl)anilino]ethyl] ester | BRD-A39918395-001-04-0 | [2-oxidanylidene-1-phenyl-2-[[3-(trifluoromethyl)phenyl]amino]ethyl] 2,5-dimethylfuran-3-carboxylate | [2-oxo-1-phenyl-2-[3-(trifluoromethyl)anilino]ethyl] 2,5-dimethylfuran-3-carboxylate | cid_4096877
Type:
Small organic molecule
Emp. Form.:
C22H18F3NO4
Mol. Mass.:
417.3778
SMILES:
Cc1cc(C(=O)OC(C(=O)Nc2cccc(c2)C(F)(F)F)c2ccccc2)c(C)o1
Structure:
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