Reaction Details Report a problem with these data
Target
Delta-type opioid receptor
Ligand
BDBM62203
Substrate
n/a
Meas. Tech.
SAR Analysis of Antagonists of the DOR Receptor using an Image-Based Assay
IC50
32000±n/a nM
Citation
 PubChem, PC SAR Analysis of Antagonists of the DOR Receptor using an Image-Based Assay PubChem Bioassay (2010)[AID] 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM62203
Synonyms:
2-(4-ketopyrrolo[1,2-a]quinoxalin-5-yl)-N-[3-[4-(4-methoxyphenyl)piperazino]propyl]acetamide | MLS-0362104.0001 | N-[3-[4-(4-methoxyphenyl)-1-piperazinyl]propyl]-2-(4-oxo-5-pyrrolo[1,2-a]quinoxalinyl)acetamide | N-[3-[4-(4-methoxyphenyl)piperazin-1-yl]propyl]-2-(4-oxidanylidenepyrrolo[1,2-a]quinoxalin-5-yl)ethanamide | N-[3-[4-(4-methoxyphenyl)piperazin-1-yl]propyl]-2-(4-oxopyrrolo[1,2-a]quinoxalin-5-yl)acetamide | cid_22522554
Type:
Small organic molecule
Emp. Form.:
C27H31N5O3
Mol. Mass.:
473.5667
SMILES:
COc1ccc(cc1)N1CCN(CCCNC(=O)Cn2c3ccccc3n3cccc3c2=O)CC1
Structure:
Search PDB for entries with ligand similarity: