Reaction Details Report a problem with these data
Target
Mu-type opioid receptor
Ligand
BDBM50090503
Substrate
n/a
Meas. Tech.
Fluorescence-based biochemical high throughput dose response assay to identify inhibitors of Protein Phosphatase 1 (PP1)
IC50
4118±n/a nM
Citation
 PubChem, PC Fluorescence-based biochemical high throughput dose response assay to identify inhibitors of Protein Phosphatase 1 (PP1) PubChem Bioassay (2010)[AID] 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50090503
Synonyms:
(1R,2S,6R,7S)-4,10-Dioxa-tricyclo[5.2.1.0*2,6*]decane-3,5-dione | (1S,2R,6S,7R)-4,10-Dioxa-tricyclo[5.2.1.0*2,6*]decane-3,5-dione | CHEMBL298246 | NORCANTHARIDIN | cid_6852411 | cid_93004
Type:
Small organic molecule
Emp. Form.:
C8H8O4
Mol. Mass.:
168.1467
SMILES:
O=C1OC(=O)[C@@H]2[C@H]3CC[C@H](O3)[C@H]12
Structure:
Search PDB for entries with ligand similarity: