Reaction Details
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Report a problem with these dataTarget
Thromboxane A2 receptor
Ligand
BDBM10042
Substrate
n/a
Ki
200±n/a nM
Comments
PDSP_4867
Citation
Armstrong, RA; Jones, RL; Wilson, NH Ligand binding to thromboxane receptors on human platelets: correlation with biological activity. Br J Pharmacol 79:953-64 (1983) [PubMed] Article More Info.:
Target
Name:
Thromboxane A2 receptor
Synonyms:
TA2R_MOUSE | Tbxa2r | Thromboxane A2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
37114.77
Organism:
MOUSE
Description:
Thromboxane A2 TBXA2R MOUSE::P30987
Residue:
341
Sequence:
MWPNGTSLGACFRPVNITLQERRAIASPWFAASFCALGLGSNLLALSVLAGARPGAGPRSSFLALLCGLVLTDFLGLLVTGAIVASQHAALLDWRATDPSCRLCYFMGVAMVFFGLCPLLLGAAMASERFVGITRPFSRPTATSRRAWATVGLVWVAAGALGLLPLLGLGRYSVQYPGSWCFLTLGTQRGDVVFGLIFALLGSASVGLSLLLNTVSVATLCRVYHTREATQRPRDCEVEMMVQLVGIMVVATVCWMPLLVFIMQTLLQTPPVMSFSGQLLRATEHQLLIYLRVATWNQILDPWVYILFRRSVLRRLHPRFSSQLQAVSLRRPPAQAMLSGP
Inhibitor
Name:
BDBM10042
Synonyms:
(5Z)-7-[(1R,4S,5R,6R)-6-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2,3-dioxabicyclo[2.2.1]heptan-5-yl]hept-5-enoic acid | (5Z,13E,15S)-9alpha, 11alpha-epidioxy-15-hydroxyprosta-5,13-dienoic acid | 9,11-epoxymethano PGH2 | PGH2 | Prostaglandin H2
Type:
Small organic molecule
Emp. Form.:
C20H32O5
Mol. Mass.:
352.4651
SMILES:
CCCCC[C@H](O)\C=C\[C@H]1[C@H]2C[C@H](OO2)[C@@H]1C\C=C/CCCC(O)=O
Structure:
