Reaction Details
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Report a problem with these dataTarget
Thromboxane A2 receptor
Ligand
BDBM82224
Substrate
n/a
Ki
320±n/a nM
Comments
PDSP_4872
Citation
Armstrong, RA; Jones, RL; Wilson, NH Ligand binding to thromboxane receptors on human platelets: correlation with biological activity. Br J Pharmacol 79:953-64 (1983) [PubMed] Article More Info.:
Target
Name:
Thromboxane A2 receptor
Synonyms:
TA2R_MOUSE | Tbxa2r | Thromboxane A2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
37114.77
Organism:
MOUSE
Description:
Thromboxane A2 TBXA2R MOUSE::P30987
Residue:
341
Sequence:
MWPNGTSLGACFRPVNITLQERRAIASPWFAASFCALGLGSNLLALSVLAGARPGAGPRSSFLALLCGLVLTDFLGLLVTGAIVASQHAALLDWRATDPSCRLCYFMGVAMVFFGLCPLLLGAAMASERFVGITRPFSRPTATSRRAWATVGLVWVAAGALGLLPLLGLGRYSVQYPGSWCFLTLGTQRGDVVFGLIFALLGSASVGLSLLLNTVSVATLCRVYHTREATQRPRDCEVEMMVQLVGIMVVATVCWMPLLVFIMQTLLQTPPVMSFSGQLLRATEHQLLIYLRVATWNQILDPWVYILFRRSVLRRLHPRFSSQLQAVSLRRPPAQAMLSGP
Inhibitor
Name:
BDBM82224
Synonyms:
CAS_188200 | ICI 79939 | NSC_188200
Type:
Small organic molecule
Emp. Form.:
C22H29FO6
Mol. Mass.:
408.4605
SMILES:
OC(COc1ccc(F)cc1)C=CC1C(O)CC(O)C1CC=CCCCC(O)=O |w:12.13,21.22|
Structure:
