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Target
Beta-lactamase
Ligand
BDBM29681
Substrate
n/a
Meas. Tech.
Counterscreen for inhibitors of TLR9-MyD88 binding: fluorescence-based cell-based high throughput dose response assay to identify non-selective inhibitors of the beta-lactamase enzyme (BLA)
IC50
2270±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of TLR9-MyD88 binding: fluorescence-based cell-based high throughput dose response assay to identify non-selective inhibitors of the beta-lactamase enzyme (BLA) PubChem Bioassay (2011)[AID] 
Target
Name:
Beta-lactamase
Synonyms:
Beta lactamase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31513.38
Organism:
Pseudomonas aeruginosa
Description:
gi_114881106
Residue:
286
Sequence:
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
  
Inhibitor
Name:
BDBM29681
Synonyms:
2-[(1,2,3,4-tetrafluoro-9-acridinyl)amino]ethanol | 2-[(1,2,3,4-tetrafluoroacridin-9-yl)amino]ethanol | 2-[[1,2,3,4-tetrakis(fluoranyl)acridin-9-yl]amino]ethanol | MLS000585711 | SMR000204274 | cid_15944846
Type:
Small organic molecule
Emp. Form.:
C15H10F4N2O
Mol. Mass.:
310.2463
SMILES:
OCCNc1c2ccccc2nc2c(F)c(F)c(F)c(F)c12
Structure:
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