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Target
Prostaglandin E2 receptor EP1 subtype
Ligand
BDBM50240166
Substrate
n/a
Meas. Tech.
ChEMBL_1667760 (CHEMBL4017648)
IC50
71±n/a nM
Citation
 Umei, K; Nishigaya, Y; Kondo, A; Tatani, K; Tanaka, N; Kohno, Y; Seto, S Novel pyrazolo[1,5-a]pyridines as orally active EP Bioorg Med Chem 25:2635-2642 (2017) [PubMed]  Article 
Target
Name:
Prostaglandin E2 receptor EP1 subtype
Synonyms:
PE2R1_RAT | Prostanoid EP1 receptor | Ptger1
Type:
Enzyme
Mol. Mass.:
43080.10
Organism:
Rattus norvegicus (Rat)
Description:
P70597
Residue:
405
Sequence:
MSPYGLNLSLVDEATTCVTPRVPNTSVVLPTGGNGTSPALPIFSMTLGAVSNVLALALLAQVAGRLRRRRSTATFLLFVASLLAIDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTQPLIHAARVSVARARLALALLAAMALAVALLPLVHVGHYELQYPGTWCFISLGPPGGWRQALLAGLFAGLGLAALLAALVCNTLSGLALLRARWRRRRSRRFRENAGPDDRRRWGSRGLRLASASSASSITSTTAALRSSRGGGSARRVHAHDVEMVGQLVGIMVVSCICWSPLLVLVVLAIGGWNSNSLQRPLFLAVRLASWNQILDPWVYILLRQAMLRQLLRLLPLRVSAKGGPTELSLTKSAWEASSLRSSRHSGFSHL
  
Inhibitor
Name:
BDBM50240166
Synonyms:
CHEMBL4060959
Type:
Small organic molecule
Emp. Form.:
C19H21ClN4O2
Mol. Mass.:
372.849
SMILES:
Cc1cc(nn1Cc1cc(Cl)cc2cc(nn12)C1CCCCC1)C(O)=O
Structure:
Search PDB for entries with ligand similarity: