Reaction Details Report a problem with these data
Target
Carbonic anhydrase 7
Ligand
BDBM50253234
Substrate
n/a
Meas. Tech.
ChEBML_1685488
Ki
1.8±n/a nM
Citation
 Angeli, A; Carta, F; Bartolucci, G; Supuran, CT Synthesis of novel acyl selenoureido benzensulfonamides as carbonic anhydrase I, II, VII and IX inhibitors. Bioorg Med Chem 25:3567-3573 (2017) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 7
Synonyms:
CA-VII | CA7 | CAH7_HUMAN | Carbonate dehydratase VII | Carbonic anhydrase | Carbonic anhydrase VII | Carbonic anhydrase VII (CA VII)
Type:
Enzyme
Mol. Mass.:
29664.11
Organism:
Homo sapiens (Human)
Description:
Human cloned isozyme.
Residue:
264
Sequence:
MTGHHGWGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELSYEACMSLSITNNGHSVQVDFNDSDDRTVVTGGPLEGPYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSCFNPKCLLPASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDERIHMVNNFRPPQPLKGRVVKASFRA
  
Inhibitor
Name:
BDBM50253234
Synonyms:
CHEMBL4101645
Type:
Small organic molecule
Emp. Form.:
C21H27N3O3SSe
Mol. Mass.:
480.48
SMILES:
CCCCCCCc1ccc(cc1)C(=O)NC(=[Se])Nc1ccc(cc1)S(N)(=O)=O
Structure:
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