Reaction Details Report a problem with these data
Target
Peptidyl-prolyl cis-trans isomerase Mip
Ligand
BDBM50263406
Substrate
n/a
Meas. Tech.
ChEBML_1697922
Ki
315±n/a nM
Citation
 Pomplun, S; Sippel, C; Hähle, A; Tay, D; Shima, K; Klages, A; Ünal, CM; Rieß, B; Toh, HT; Hansen, G; Yoon, HS; Bracher, A; Preiser, P; Rupp, J; Steinert, M; Hausch, F Chemogenomic Profiling of Human and Microbial FK506-Binding Proteins. J Med Chem 61:3660-3673 (2018) [PubMed]  Article 
Target
Name:
Peptidyl-prolyl cis-trans isomerase Mip
Synonyms:
5.2.1.8 | MIP_CHLPN | PPIase | Peptidyl-prolyl cis-trans isomerase Mip | Rotamase | mip
Type:
PROTEIN
Mol. Mass.:
28326.39
Organism:
Chlamydia pneumoniae
Description:
ChEMBL_117367
Residue:
258
Sequence:
MNRRWNLVLATVALALSVASCDVRSKDKDKDQGSLVEYKDNKDTNDIELSDNQKLSRTFGHLLARQLRKSEDMFFDIAEVAKGLQAELVCKSAPLTETEYEEKMAEVQKLVFEKKSKENLSLAEKFLKENSKNAGVVEVQPSKLQYKIIKEGAGKAISGKPSALLHYKGSFINGQVFSSSEGNNEPILLPLGQTIPGFALGMQGMKEGETRVLYIHPDLAYGTAGQLPPNSLLIFEINLIQASADEVAAVPQEGNQGE
  
Inhibitor
Name:
BDBM50263406
Synonyms:
CHEMBL4089167
Type:
Small organic molecule
Emp. Form.:
C21H22Cl2N2O4S
Mol. Mass.:
469.381
SMILES:
[H][C@]12CCC[C@]([H])(N1S(=O)(=O)c1cc(Cl)cc(Cl)c1)C(=O)N(Cc1ccco1)C[C@@H]2C=C |r,TLB:20:19:7:2.3.4,30:29:7:2.3.4,THB:22:21:7:2.3.4|
Structure:
Search PDB for entries with ligand similarity: