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Target
Neutrophil elastase
Ligand
BDBM50278949
Substrate
n/a
Meas. Tech.
ChEMBL_1719625 (CHEMBL4134625)
IC50
>100000±n/a nM
Citation
 Ryu, HW; Park, YJ; Lee, SU; Lee, S; Yuk, HJ; Seo, KH; Kim, YU; Hwang, BY; Oh, SR Potential Anti-inflammatory Effects of the Fruits of Paulownia tomentosa. J Nat Prod 80:2659-2665 (2017) [PubMed]  Article 
Target
Name:
Neutrophil elastase
Synonyms:
Bone marrow serine protease | Chymotrypsin | Coagulation factor X | ELA2 | ELANE | ELNE_HUMAN | Elastase | Elastase-2 | HLE | Human leukocyte elastase | Leukocyte elastase | Leukocyte elastase (HLE) | Medullasin | Neutrophil elastase | Neutrophil elastase (HNE) | Neutrophil elastase (NE) | PMN elastase | Thrombin | Trypsin
Type:
Enzyme
Mol. Mass.:
28532.38
Organism:
Homo sapiens (Human)
Description:
P08246
Residue:
267
Sequence:
MTLGRRLACLFLACVLPALLLGGTALASEIVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNLSRREPTRQVFAVQRIFENGYDPVNLLNDIVILQLNGSATINANVQVAQLPAQGRRLGNGVQCLAMGWGLLGRNRGIASVLQELNVTVVTSLCRRSNVCTLVRGRQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQRSEDNPCPHPRDPDPASRTH
  
Inhibitor
Name:
BDBM50278949
Synonyms:
CHEMBL2387712
Type:
Small organic molecule
Emp. Form.:
C26H32O7
Mol. Mass.:
456.5281
SMILES:
COc1ccc(cc1O)[C@@H]1CC(=O)c2c(O)c3CCC(C)(CCCC(C)(C)O)Oc3cc2O1 |r|
Structure:
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