Reaction Details Report a problem with these data
Target
Free fatty acid receptor 1
Ligand
BDBM50453343
Substrate
n/a
Meas. Tech.
ChEMBL_1749938 (CHEMBL4184698)
EC50
1411±n/a nM
Citation
  TBA Bioorg Med Chem Lett 28:429-436 (2018) [PubMed]  Article 
Target
Name:
Free fatty acid receptor 1
Synonyms:
FFAR1 | FFAR1_HUMAN | G-protein Coupled Receptor 40 | GPR40
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
31473.32
Organism:
Homo sapiens (Human)
Description:
O14842
Residue:
300
Sequence:
MDLPPQLSFGLYVAAFALGFPLNVLAIRGATAHARLRLTPSLVYALNLGCSDLLLTVSLPLKAVEALASGAWPLPASLCPVFAVAHFFPLYAGGGFLAALSAGRYLGAAFPLGYQAFRRPCYSWGVCAAIWALVLCHLGLVFGLEAPGGWLDHSNTSLGINTPVNGSPVCLEAWDPASAGPARFSLSLLLFFLPLAITAFCYVGCLRALARSGLTHRRKLRAAWVAGGALLTLLLCVGPYNASNVASFLYPNLGGSWRKLGLITGAWSVVLNPLVTGYLGRGPGLKTVCAARTQGGKSQK
  
Inhibitor
Name:
BDBM50453343
Synonyms:
CHEMBL4211335
Type:
Small organic molecule
Emp. Form.:
C28H24N4O2S
Mol. Mass.:
480.581
SMILES:
CC#C[C@@H](Cc1nnn[nH]1)c1ccc(OCc2ccc3[S+]([O-])C=C(c3c2)c2ccccc2C)cc1 |r,c:23|
Structure:
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