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Target
Cysteinyl leukotriene receptor 1
Ligand
BDBM50021780
Substrate
n/a
Meas. Tech.
ChEBML_52214
Ki
60±n/a nM
Citation
 Gleason, JG; Hall, RF; Perchonock, CD; Erhard, KF; Frazee, JS; Ku, TW; Kondrad, K; McCarthy, ME; Mong, S; Crooke, ST High-affinity leukotriene receptor antagonists. Synthesis and pharmacological characterization of 2-hydroxy-3-[(2-carboxyethyl)thio]-3-[2-(8-phenyloctyl)phenyl] propanoic acid. J Med Chem 30:959-61 (1987) [PubMed]  Article 
Target
Name:
Cysteinyl leukotriene receptor 1
Synonyms:
CLTR1_CAVPO | CYSLTR1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
39007.58
Organism:
GUINEA PIG
Description:
Leukotriene D4 0 GUINEA PIG::Q2NNR5
Residue:
340
Sequence:
MDETGNPTIPPASNNTCYDSIDDFRNQVYSTLYSMISVVGFFGNGFVLYVLVKTYHEKSAFQVYMINLAVADLLCVCTLPLRVAYYVHKGIWLFGDFLCRLSTYALYVNLYCSIFFMTAMSFFRCVAIVFPVQNISLVTQKKARLVCIAIWMFVILTSSPFLMANTYKDEKNNTKCFEPPQDNQAKNYVLILHYVSLFIGFIIPFITIIVCYTMIIFTLLKSSMKKNLSSRKRAIGMIIVVTAAFLVSFMPYHIQRTIHLHFLHNKTKPCDSILRMQKSVVITLSLAASNCCFDPLLYFFSGGNFRRRLSTIRKYSLSSMTYIPKKKTSLPQKGKDICKE
  
Inhibitor
Name:
BDBM50021780
Synonyms:
3-(2-Carboxy-ethylsulfanyl)-3-[2-(8-phenyl-octyl)-phenyl]-propionic acid | CHEMBL175401
Type:
Small organic molecule
Emp. Form.:
C26H34O4S
Mol. Mass.:
442.611
SMILES:
OC(=O)CCSC(CC(O)=O)c1ccccc1CCCCCCCCc1ccccc1
Structure:
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