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Target
Reverse transcriptase
Ligand
BDBM50483004
Substrate
n/a
Meas. Tech.
ChEMBL_675251 (CHEMBL1273233)
IC50
>100000±n/a nM
Citation
 Liu, B; Lee, Y; Zou, J; Petrassi, HM; Joseph, RW; Chao, W; Michelotti, EL; Bukhtiyarova, M; Springman, EB; Dorsey, BD Discovery and SAR of a series of 4,6-diamino-1,3,5-triazin-2-ol as novel non-nucleoside reverse transcriptase inhibitors of HIV-1. Bioorg Med Chem Lett 20:6592-6 (2010) [PubMed]  Article 
Target
Name:
Reverse transcriptase
Synonyms:
n/a
Type:
Protein
Mol. Mass.:
29598.37
Organism:
Human immunodeficiency virus 1
Description:
Q9WKE8
Residue:
254
Sequence:
PISPITVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKIEKIGPENPYNTPVFAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIEQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVN
  
Inhibitor
Name:
BDBM50483004
Synonyms:
CHEMBL1270345
Type:
Small organic molecule
Emp. Form.:
C24H17ClFN5O
Mol. Mass.:
445.876
SMILES:
Fc1cccc(-c2ccccc2)c1Nc1nc(Cl)nc(NCc2ccc3occc3c2)n1
Structure:
Search PDB for entries with ligand similarity: