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Target
Mu-type opioid receptor
Ligand
BDBM50500610
Substrate
n/a
Meas. Tech.
ChEMBL_1548303 (CHEMBL3755754)
IC50
1005±n/a nM
Citation
 Deekonda, S; Cole, J; Sunna, S; Rankin, D; Largent-Milnes, TM; Davis, P; BassiriRad, NM; Lai, J; Vanderah, TW; Porecca, F; Hruby, VJ Enkephalin analogues with N-phenyl-N-(piperidin-2-ylmethyl)propionamide derivatives: Synthesis and biological evaluations. Bioorg Med Chem Lett 26:222-7 (2016) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO
Type:
Enzyme Catalytic Domain
Mol. Mass.:
11165.58
Organism:
GUINEA PIG
Description:
P97266
Residue:
98
Sequence:
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
  
Inhibitor
Name:
BDBM50500610
Synonyms:
CHEMBL3754245
Type:
Small organic molecule
Emp. Form.:
C26H35N3O
Mol. Mass.:
405.5756
SMILES:
CCC(=O)N(CC1CCCCN1Cc1ccc2[C@H](N)CCCc2c1)c1ccccc1 |r|
Structure:
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