Reaction Details Report a problem with these data
Target
Melatonin receptor type 1A
Ligand
BDBM50035202
Substrate
n/a
Meas. Tech.
ChEMBL_105104 (CHEMBL715948)
Ki
0.099000±n/a nM
Citation
 Witt-Enderby, PA; Chu, GH; Gillen, ML; Li, PK Development of a high-affinity ligand that binds irreversibly to Mel1b melatonin receptors. J Med Chem 40:4195-8 (1998) [PubMed]  Article 
Target
Name:
Melatonin receptor type 1A
Synonyms:
MTNR1A | MTNR1A protein | MTR1A_HUMAN | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A
Type:
Enzyme
Mol. Mass.:
39392.94
Organism:
Homo sapiens (Human)
Description:
P48039
Residue:
350
Sequence:
MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRNAGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITGIAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFAQSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTMFVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQNFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
  
Inhibitor
Name:
BDBM50035202
Synonyms:
CHEMBL291857 | N-[2-(2,7-Dimethoxy-naphthalen-1-yl)-ethyl]-propionamide
Type:
Small organic molecule
Emp. Form.:
C17H21NO3
Mol. Mass.:
287.3535
SMILES:
CCC(=O)NCCc1c(OC)ccc2ccc(OC)cc12
Structure:
Search PDB for entries with ligand similarity: