Reaction Details Report a problem with these data
Target
Melatonin receptor type 1B
Ligand
BDBM50061569
Substrate
n/a
Meas. Tech.
ChEMBL_105269 (CHEMBL713141)
Ki
1.6±n/a nM
Citation
 Witt-Enderby, PA; Chu, GH; Gillen, ML; Li, PK Development of a high-affinity ligand that binds irreversibly to Mel1b melatonin receptors. J Med Chem 40:4195-8 (1998) [PubMed]  Article 
Target
Name:
Melatonin receptor type 1B
Synonyms:
MTNR1B | MTR1B_HUMAN | Mel-1B-R | Mel1b melatonin receptor | Melatonin 1B | Melatonin receptor | Melatonin receptor type 1B | Melatonin receptor type 2 (MT2)
Type:
Enzyme
Mol. Mass.:
40203.54
Organism:
Homo sapiens (Human)
Description:
P49286
Residue:
362
Sequence:
MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLLVILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVMGLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGSLEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRLCLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFNSCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQADAL
  
Inhibitor
Name:
BDBM50061569
Synonyms:
CHEMBL131919 | Chloro-acetic acid 7-methoxy-1-(2-propionylamino-ethyl)-naphthalen-2-yl ester
Type:
Small organic molecule
Emp. Form.:
C18H20ClNO4
Mol. Mass.:
349.809
SMILES:
CCC(=O)NCCc1c(OC(=O)CCl)ccc2ccc(OC)cc12
Structure:
Search PDB for entries with ligand similarity: