Target
Reverse transcriptase
Ligand
BDBM50524091
Substrate
n/a
Meas. Tech.
ChEMBL_1891830 (CHEMBL4393751)
IC50
6000±n/a nM
Citation
 Namasivayam, VVanangamudi, MKramer, VGKurup, SZhan, PLiu, XKongsted, JByrareddy, SN The Journey of HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs) from Lab to Clinic. J Med Chem 62:4851-4883 (2019) [PubMed]  Article 
Target
Name:
Reverse transcriptase
Synonyms:
n/a
Type:
Protein
Mol. Mass.:
29598.37
Organism:
Human immunodeficiency virus 1
Description:
Q9WKE8
Residue:
254
Sequence:
PISPITVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKIEKIGPENPYNTPVFAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPLDKDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIVIYQYMDDLYVGSDLEIEQHRAKIEELRQHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWTVQPIVLPEKDSWTVN
  
Inhibitor
Name:
BDBM50524091
Synonyms:
CHEMBL307792
Type:
Small organic molecule
Emp. Form.:
C12H9N3O
Mol. Mass.:
211.2194
SMILES:
O=C1Nc2cccnc2Nc2ccccc12
Structure:
Search PDB for entries with ligand similarity: