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Target
Nonstructural protein 3
Ligand
BDBM50528561
Substrate
n/a
Meas. Tech.
ChEMBL_1905425 (CHEMBL4407783)
IC50
3500±n/a nM
Citation
 Rassias, G; Zogali, V; Swarbrick, CMD; Ki Chan, KW; Chan, SA; Gwee, CP; Wang, S; Kaplanai, E; Canko, A; Kiousis, D; Lescar, J; Luo, D; Matsoukas, MT; Vasudevan, SG Cell-active carbazole derivatives as inhibitors of the zika virus protease. Eur J Med Chem 180:536-545 (2019) [PubMed]  Article 
Target
Name:
Nonstructural protein 3
Synonyms:
Genome polyprotein | NS3
Type:
PROTEIN
Mol. Mass.:
7653.58
Organism:
Zika virus
Description:
ChEMBL_119671
Residue:
66
Sequence:
AETDEDHAHWLEARMLLDNIYLQDGLIASLYRPEADKVAAIEGEFKLRTEQRKTFVELMKRGDLPV
  
Inhibitor
Name:
BDBM50528561
Synonyms:
CHEMBL4518903
Type:
Small organic molecule
Emp. Form.:
C33H21N5O2S
Mol. Mass.:
551.617
SMILES:
NC(=N)c1cccc(c1)S(=O)(=O)n1c2ccc(cc2c2cc(ccc12)-c1cccc(c1)C#N)-c1cccc(c1)C#N
Structure:
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