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Target
Kappa-type opioid receptor
Ligand
BDBM50093962
Substrate
n/a
Meas. Tech.
ChEBML_145268
Ki
0.130000±n/a nM
Citation
 Kumar, V; Marella, MA; Cortes-Burgos, L; Chang, AC; Cassel, JA; Daubert, JD; DeHaven, RN; DeHaven-Hudkins, DL; Gottshall, SL; Mansson, E; Maycock, AL Arylacetamides as peripherally restricted kappa opioid receptor agonists. Bioorg Med Chem Lett 10:2567-70 (2001) [PubMed]  Article 
Target
Name:
Kappa-type opioid receptor
Synonyms:
K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42648.76
Organism:
Homo sapiens (Human)
Description:
P41145
Residue:
380
Sequence:
MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRVRNTVQDPAYLRDIDGMNKPV
  
Inhibitor
Name:
BDBM50093962
Synonyms:
CHEMBL87306 | N-Methyl-N-((S)-1-phenyl-2-pyrrolidin-1-yl-ethyl)-2-(2-trifluoromethyl-phenyl)-acetamide
Type:
Small organic molecule
Emp. Form.:
C22H25F3N2O
Mol. Mass.:
390.4419
SMILES:
CN([C@H](CN1CCCC1)c1ccccc1)C(=O)Cc1ccccc1C(F)(F)F
Structure:
Search PDB for entries with ligand similarity: