Reaction Details Report a problem with these data
Target
Group 10 secretory phospholipase A2
Ligand
BDBM50101027
Substrate
n/a
Meas. Tech.
ChEBML_155888
IC50
10000±n/a nM
Citation
 Liu, Y; Feng, Y; Wang, R; Gao, Y; Lai, L Quinoline-4-acetamides as sPLA(2) inhibitors. Bioorg Med Chem Lett 11:1639-41 (2001) [PubMed]  Article 
Target
Name:
Group 10 secretory phospholipase A2
Synonyms:
Group X secretory phospholipase A2 | PA2GX_HUMAN | PLA2G10
Type:
PROTEIN
Mol. Mass.:
18153.11
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1442449
Residue:
165
Sequence:
MGPLPVCLPIMLLLLLPSLLLLLLLPGPGSGEASRILRVHRRGILELAGTVGCVGPRTPIAYMKYGCFCGLGGHGQPRDAIDWCCHGHDCCYTRAEEAGCSPKTERYSWQCVNQSVLCGPAENKCQELLCKCDQEIANCLAQTEYNLKYLFYPQFLCEPDSPKCD
  
Inhibitor
Name:
BDBM50101027
Synonyms:
6-Methoxy-2-phenoxy-quinoline-4-carboxylic acid amide | CHEMBL43367
Type:
Small organic molecule
Emp. Form.:
C17H14N2O3
Mol. Mass.:
294.3047
SMILES:
COc1ccc2nc(Oc3ccccc3)cc(C(N)=O)c2c1
Structure:
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