Reaction Details Report a problem with these data
Target
Translocator protein
Ligand
BDBM50000766
Substrate
n/a
Meas. Tech.
ChEMBL_2237060 (CHEMBL5150956)
Ki
0.900000±n/a nM
Citation
 Robello, M; Barresi, E; Baglini, E; Salerno, S; Taliani, S; Settimo, FD The Alpha Keto Amide Moiety as a Privileged Motif in Medicinal Chemistry: Current Insights and Emerging Opportunities. J Med Chem 64:3508-3545 (2021) [PubMed] 
Target
Name:
Translocator protein
Synonyms:
BZRP | IBP | Isoquinoline-binding protein | PBR | PKBS | Peripheral-type benzodiazepine receptor | TSPO | TSPO_BOVIN
Type:
PROTEIN
Mol. Mass.:
18933.98
Organism:
Bos taurus
Description:
ChEMBL_10840
Residue:
169
Sequence:
MAPPWVPAVGFTLLPSLGGFLGAQYTRGEGFRWYASLQKPPWHPPRWILAPIWGTLYSAMGYGSYMIWKELGGFSKEAVVPLGLYAGQLALNWAWPPLFFGTRQMGWALVDLLLTGGMAAATAMAWHQVSPPAACLLYPYLAWLAFAGMLNYRMWQDNQVRRSGRRLSE
  
Inhibitor
Name:
BDBM50000766
Synonyms:
CHEMBL12 | DIAZEPAM | US9271961, Diazepam
Type:
Small organic molecule
Emp. Form.:
C16H13ClN2O
Mol. Mass.:
284.74
SMILES:
CN1c2ccc(Cl)cc2C(=NCC1=O)c1ccccc1 |c:10|
Structure:
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