Reaction Details Report a problem with these data
Target
Prostaglandin D2 receptor
Ligand
BDBM50213925
Substrate
n/a
Meas. Tech.
ChEMBL_456179 (CHEMBL888189)
Ki
4740±n/a nM
Citation
 Sandham, DA; Aldcroft, C; Baettig, U; Barker, L; Beer, D; Bhalay, G; Brown, Z; Dubois, G; Budd, D; Bidlake, L; Campbell, E; Cox, B; Everatt, B; Harrison, D; Leblanc, CJ; Manini, J; Profit, R; Stringer, R; Thompson, KS; Turner, KL; Tweed, MF; Walker, C; Watson, SJ; Whitebread, S; Willis, J; Williams, G; Wilson, C 2-Cycloalkyl phenoxyacetic acid CRTh2 receptor antagonists. Bioorg Med Chem Lett 17:4347-50 (2007) [PubMed]  Article 
Target
Name:
Prostaglandin D2 receptor
Synonyms:
PD2R_HUMAN | PTGDR | Prostaglandin D2 | Prostaglandin D2 receptor | Prostanoid DP receptor
Type:
Enzyme
Mol. Mass.:
40288.87
Organism:
Homo sapiens (Human)
Description:
Q13258
Residue:
359
Sequence:
MKSPFYRCQNTTSVEKGNSAVMGGVLFSTGLLGNLLALGLLARSGLGWCSRRPLRPLPSVFYMLVCGLTVTDLLGKCLLSPVVLAAYAQNRSLRVLAPALDNSLCQAFAFFMSFFGLSSTLQLLAMALECWLSLGHPFFYRRHITLRLGALVAPVVSAFSLAFCALPFMGFGKFVQYCPGTWCFIQMVHEEGSLSVLGYSVLYSSLMALLVLATVLCNLGAMRNLYAMHRRLQRHPRSCTRDCAEPRADGREASPQPLEELDHLLLLALMTVLFTMCSLPVIYRAYYGAFKDVKEKNRTSEEAEDLRALRFLSVISIVDPWIFIIFRSPVFRIFFHKIFIRPLRYRSRCSNSTNMESSL
  
Inhibitor
Name:
BDBM50213925
Synonyms:
2-(2-allyl-4-chlorophenoxy)acetic acid | CHEMBL245707
Type:
Small organic molecule
Emp. Form.:
C11H11ClO3
Mol. Mass.:
226.656
SMILES:
OC(=O)COc1ccc(Cl)cc1CC=C
Structure:
Search PDB for entries with ligand similarity: