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Target
Transcriptional activator protein LuxR
Ligand
BDBM50262465
Substrate
n/a
Meas. Tech.
ChEMBL_490917 (CHEMBL989193)
IC50
55000±n/a nM
Citation
 Estephane, J; Dauvergne, J; Soulère, L; Reverchon, S; Queneau, Y; Doutheau, A N-Acyl-3-amino-5H-furanone derivatives as new inhibitors of LuxR-dependent quorum sensing: Synthesis, biological evaluation and binding mode study. Bioorg Med Chem Lett 18:4321-4 (2008) [PubMed]  Article 
Target
Name:
Transcriptional activator protein LuxR
Synonyms:
LUXR_ALIFS | luxR
Type:
PROTEIN
Mol. Mass.:
28563.86
Organism:
Vibrio fischeri
Description:
ChEMBL_831639
Residue:
250
Sequence:
MKNINADDTYRIINKIKACRSNNDINQCLSDMTKMVHCEYYLLAIIYPHSMVKSDISILDNYPKKWRQYYDDANLIKYDPIVDYSNSNHSPINWNIFENNAVNKKSPNVIKEAKTSGLITGFSFPIHTANNGFGMLSFAHSEKDNYIDSLFLHACMNIPLIVPSLVDNYRKINIANNKSNNDLTKREKECLAWACEGKSSWDISKILGCSERTVTFHLTNAQMKLNTTNRCQSISKAILTGAIDCPYFKN
  
Inhibitor
Name:
BDBM50262465
Synonyms:
3-oxo-N-(2-oxo-2,5-dihydrofuran-3-yl)hexanamide | CHEMBL477585
Type:
Small organic molecule
Emp. Form.:
C10H13NO4
Mol. Mass.:
211.2145
SMILES:
CCCC(=O)CC(=O)NC1=CCOC1=O |t:9|
Structure:
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