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Target
Gag-Pol polyprotein [489-587]
Ligand
BDBM81
Substrate
n/a
Meas. Tech.
ChEBML_79984
Ki
34±n/a nM
Citation
 Smallheer, JM; McHugh, RJ; Chang, CH; Kaltenbach, RF; Worley, TV; Klabe, RM; Bacheler, LT; Rayner, MM; Erickson-Viitanen, S; Seitz, SP Functionalized aliphatic P2/P2′ analogs of HIV-1 protease inhibitor DMP323 Bioorg Med Chem Lett 7:1365-1370 (1997)    Article 
Target
Name:
Gag-Pol polyprotein [489-587]
Synonyms:
Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol
Type:
Enzyme Subunit
Mol. Mass.:
10781.16
Organism:
Human immunodeficiency virus type 1
Description:
P04585[489-587]
Residue:
99
Sequence:
PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYDQILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
  
Inhibitor
Name:
BDBM81
Synonyms:
(4R,5S,6S,7R)-4,7-dibenzyl-5,6-dihydroxy-1,3-bis(7-hydroxyheptyl)-1,3-diazepan-2-one | DMPC Cyclic Urea 61
Type:
n/a
Emp. Form.:
C33H50N2O5
Mol. Mass.:
554.7605
SMILES:
OCCCCCCCN1[C@H](Cc2ccccc2)[C@H](O)[C@@H](O)[C@@H](Cc2ccccc2)N(CCCCCCCO)C1=O
Structure:
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