Reaction Details Report a problem with these data
Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM50324099
Substrate
n/a
Meas. Tech.
ChEMBL_649647 (CHEMBL1219345)
Ki
5.2±n/a nM
Citation
 Moussa, IA; Banister, SD; Beinat, C; Giboureau, N; Reynolds, AJ; Kassiou, M Design, synthesis, and structure-affinity relationships of regioisomeric N-benzyl alkyl ether piperazine derivatives as sigma-1 receptor ligands. J Med Chem 53:6228-39 (2010) [PubMed]  Article 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
Opioid receptor | Oprs1 | SGMR1_RAT | Sigma | Sigma non-opioid intracellular receptor 1 | Sigma opioid receptor | Sigma-1 | Sigmar1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25266.54
Organism:
RAT
Description:
Q9R0C9
Residue:
223
Sequence:
MPWAVGRRWAWITLFLTIVAVLIQAVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSRLIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSHGHSGRYWAEISDTIISGTFHQWREGTTKSEVYYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLAFALSDTIFSTQDFLTLFYTLRAYARGLRLELTTYLFGQDP
  
Inhibitor
Name:
BDBM50324099
Synonyms:
CHEMBL1214829 | N-((Benzofuran-2-yl)methyl)-N'-benzylpiperazine
Type:
Small organic molecule
Emp. Form.:
C20H22N2O
Mol. Mass.:
306.4015
SMILES:
C(N1CCN(Cc2ccccc2)CC1)c1cc2ccccc2o1
Structure:
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