Reaction Details Report a problem with these data
Target
Sortase family protein
Ligand
BDBM50331603
Substrate
n/a
Meas. Tech.
ChEMBL_687441 (CHEMBL1292117)
IC50
174000±n/a nM
Citation
 Lee, YJ; Han, YR; Park, W; Nam, SH; Oh, KB; Lee, HS Synthetic analogs of indole-containing natural products as inhibitors of sortase A and isocitrate lyase. Bioorg Med Chem Lett 20:6882-5 (2010) [PubMed]  Article 
Target
Name:
Sortase family protein
Synonyms:
Sortase | Sortase A (SrtA)
Type:
Enzyme
Mol. Mass.:
23546.15
Organism:
Staphylococcus aureus
Description:
n/a
Residue:
206
Sequence:
MKKWTNRLMTIAGVVLILVAAYLFAKPHIDNYLHDKDKDEKIEQYDKNVKEQASKDKKQQAKPQIPKDKSKVAGYIEIPDADIKEPVYPGPATPEQLNRGVSFAEENESLDDQNISIAGHTFIDRPNYQFTNLKAAKKGSMVYFKVGNETRKYKMTSIRDVKPTDVGVLDEQKGKDKQLTLITCDDYNEKTGVWEKRKIFVATEVK
  
Inhibitor
Name:
BDBM50331603
Synonyms:
2-(1H-Indol-3-yl)-2-oxo-N-phenyl-acetamide | 2-(1H-indol-3-yl)-2-oxo-N-phenylacetamide | CHEMBL356828 | cid_3149448
Type:
Small organic molecule
Emp. Form.:
C16H12N2O2
Mol. Mass.:
264.2787
SMILES:
O=C(Nc1ccccc1)C(=O)c1c[nH]c2ccccc12
Structure:
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